Comparative Effectiveness of Generic Atorvastatin and Lipitor(R) in Patients Hospitalized with an Acute Coronary Syndrome Health Services and Outcomes Research

Conclusions Among older adults discharged alive after ACS hospitalization, we found no significant difference in cardiovascular outcomes or serious, infrequent side effects in patients prescribed generic atorvastatin compared with those prescribed Lipitor® at 1 year. Our findings support the use of generic atorvastatin in ACS, which could lead to substantial cost saving for patients and health care plans without diminishing population clinical effectiveness.
Source: JAHA:Journal of the American Heart Association - Category: Cardiology Authors: Tags: Atrial Fibrillation, Quality and Outcomes Health Services and Outcomes Research Source Type: research

Related Links:

BACKGROUND: Fatigue and sleep disturbance are common and debilitating problems after brain injury. Light therapy shows promise as a potential treatment. We conducted a trial of in-home light therapy to alleviate fatigue and sleep disturbance. The aim of th...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Program and Other Evaluations, Effectiveness Studies Source Type: news
This study showed the association between atrial fibrillation and increased risk of incident fracture. The relationship between atri...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
BMJ Open Diabetes Res Care. 2021 Aug;9(1):e002296. doi: 10.1136/bmjdrc-2021-002296.ABSTRACTINTRODUCTION: Zinc transporter 8 autoantibodies (ZnT8A) are biomarkers of beta cell autoimmunity in type 1 diabetes that have become more widely available to clinicians in recent years. Robust control population-defined thresholds are essential to ensure high clinical specificity in islet autoantibody testing. We aimed to determine the optimal cut-offs for ZnT8A testing.RESEARCH DESIGN AND METHODS: 97.5th and 99th centile cut-offs were determined using residual clinical sera from 1559 controls aged between 0 and 83 years with no hist...
Source: Cell Research - Category: Cytology Authors: Source Type: research
CONCLUSIONS: The present study reveals that high glucose condition directly affects retinal endothelial cells (EC) function, and O-GlcNAc modification is critical for the proliferation and migration of HRMECs, RUNX1 may take part in this mechanism, and maybe the function of RUNX1 is related to its O-GlcNAc modification level, which provides a new perspective for studying the mechanism of RUNX1 in diabetic retinopathy.PMID:34348917 | DOI:10.1136/bmjdrc-2020-001898
Source: Cell Research - Category: Cytology Authors: Source Type: research
A pilot program conducted in New York City has shown that a mobile interventiona...Read more on AuntMinnie.comRelated Reading: LVO stroke patients benefit from going directly to angiography suite 'Redundant imaging' for TIA workup increases in the ED Stroke care drops in early months of pandemic CT mobile stroke units improve patient outcomes NeuroLogica launches new mobile stroke CT scanner
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
AbstractThe seminiferous tubules where spermatogenesis occurs are enveloped and protected by the Sertoli cells to support germ cells undergoing meiosis to produce haploid gametes. Clearly, induction of apoptosis in seminiferous tubules leads to abnormalities in spermatogenesis and male infertility. Studies demonstrated that increased hyperlipidemia impairs male infertility and spermatogenesis by enhancing seminiferous tubules apoptosis. However, molecular mechanisms underlying high-cholesterol-mediated testicular damage remain poorly elucidated. In this scope, we established a rabbit model and investigated the role of endo...
Source: IUBMB Life - Category: Research Authors: Tags: SPECIAL ISSUE Source Type: research
Is oral secretagogue treatment a safe and effective alternative to daily injectables for children with growth disorders?Journal of the Endocrine Society
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
Might cardiac biomarkers such as NT-proBNP, hs-cTnT and GDF-15 be useful for identifying patients at risk of cognitive decline, adverse cerebrovascular events and mortality?Stroke
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news
DIABETES type 2 is a chronic condition that can prove life-threatening if high blood sugar levels are not tamed. A telltale sign in your foot can signal high blood sugar levels are putting you at risk of amputation, warned Doctor Prash Vas, Consultant in Diabetes and Diabetes Food Medicine at London Bridge Hospital .
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
HIGH CHOLESTEROL levels can lead to major health woes, having unhealthy levels can potentially be fatal - how do you know if your levels are dangerously high?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
More News: Atorvastatin Calcium | Atrial Fibrillation | Cardiology | Cardiovascular | Cholesterol | Diabetes | Endocrinology | Health | Health Management | Heart | Heart Attack | Heart Failure | Lipitor | Renal Failure | Rhabdomyolysis | Statin Therapy | Stroke | Study | Zivast