Nuclear Imaging for Assessment of Myocardial Perfusion, Metabolism, and Innervation in Hypertrophic Cardiomyopathy

Abstract Purpose of Review Hypertrophic cardiomyopathy, the most common genetic disease of the heart, is characterized by diverse cardiac phenotypic expression, presentation, clinical course, response to therapy, and outcomes. Disease causing mutations, genetic modifiers, and environmental factors are responsible for the diversity of morphological and clinical manifestations of this disease. Recent Findings Over the last four decades, cardiac nuclear imaging has made crucial contributions to our current understanding of the pathophysiology of HCM and has provided clinical tools for targeted management of patients. Summary The aim of this manuscript is to review the role of nuclear imaging in assessment of myocardial perfusion, metabolism, and autonomic innervation in HCM.
Source: Current Cardiovascular Imaging Reports - Category: Radiology Source Type: research