Log in to search using one of your social media accounts:

 

Negative sestamibi scan for primary hyperparathyroidism can mean no referral or surgery

BALTIMORE – In the treatment of primary hyperparathyroidism, clinical guidelines recommend using sestamibi scan for localizing adenoma, but increasingly endocrinologists are using sestamibi results...
Source: Clinical Endocrinology News - Category: Endocrinology Source Type: news

Related Links:

99mTc sestamibi parathyroid scan was performed in a 35-year-old man with chronic renal failure to evaluate the cause of increased serum parathyroid hormone. Both early and delayed images showed intense activity overlapping the left upper pole of the thyroid, which was proven to be nodular parathyroid hyperplasia after parathyroidectomy. However, the levels of serum parathyroid hormone remained elevated postsurgically. A repeat sestamibi study revealed abnormal activity in the left upper mediastinum, which could also be subtly seen on initial sestamibi study. A retrosternal lesion was resected, which was confirmed as an ect...
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
AbstractBackgroundCriteria for diagnosing primary hyperparathyroidism (PHPT) include hypercalcemia in the presence of parathyroid hormone (PTH) levels that are either elevated (classic PHPT) or normal but non-suppressed. However, there is no standard definition of what constitutes normal non-suppressed levels, and data are lacking regarding the potential for surgical cure in these patients.MethodsA retrospective review of patients undergoing parathyroidectomy for sporadic PHPT between 2012 and 2014 was performed. Patients with normal PTH were compared to classic PHPT patients to assess demographics, imaging, operative find...
Source: World Journal of Surgery - Category: Surgery Source Type: research
Dr. Hiebert and co-authors have done an excellent study and written an excellent manuscript. The strength of their work has been a very thorough evaluation of a new novel technology, dual energy computed tomography, and comparison with cervical ultrasound and sestamibi scan, currently the commonest pair of techniques for localization and planning for surgery in patients with hyperparathyroidism. Most imaging reports for preoperative parathyroid localization focus on images and only one technology.
Source: American Journal of Surgery - Category: Surgery Authors: Source Type: research
In this study, the authors reported a discordance rate of 29.9% using parathyroid 4-dimensional computed tomography ( 4D-CT) as the sole preoperative imaging modality in primary hyperparathyroidism (and a rate of 25% if surgeon-led ultrasonography [US] and 4D-CT were combined). In addition, they conducted a thorough analysis of putative factors contributing to this inaccuracy.
Source: JAMA Surgery - Category: Sports Medicine Source Type: research
99mTc sestamibi parathyroid scan was performed in a 35-year-old man with chronic renal failure to evaluate the cause of increased serum parathyroid hormone. Both early and delayed images showed intense activity overlapping the left upper pole of the thyroid, which was proven to be nodular parathyroid hyperplasia after parathyroidectomy. However, the levels of serum parathyroid hormone remained elevated postsurgically. A repeat sestamibi study revealed abnormal activity in the left upper mediastinum, which could also be subtly seen on initial sestamibi study. A retrosternal lesion was resected, which was confirmed as an ect...
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Primary hyperparathyroidism is caused by single gland disease in 85% of cases and by multiglandular disease in 15%. Our aim was to discover if the addition of computed tomography acquisition/fusion on a hybrid scanner to traditional dual-phase single-photon emission tomography improves localization accuracy.
Source: Surgery - Category: Surgery Authors: Source Type: research
O Kandemir, P Atmaca Kelkit, K KarakuşNigerian Journal of Clinical Practice 2017 20(11):1510-1512 Simultaneous existence of parathyroid adenoma and thyroid nonmedullary carcinoma is rarely observed. A 52-year-old female was diagnosed approximately 4 years ago with primary hyperparathyroidism (PHPT) on the basis of hypercalcemia and elevated serum parathyroid hormone (PTH) level. Clinically, PHPT diagnosed patient was examined with Tc-99m MIBI scintigraphy to investigate parathyroid adenoma. Early Tc-99m MIBI images showed focal focused enhanced activity retention on both thyroid left lobe upper pole and thyroid lower...
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research
An elderly lady was diagnosed with primary hyperparathyroidism after being admitted to hospital with pyelonephritis and constipation. A sestamibi parathyroid scan demonstrated increased uptake in the upper mediastinum, suggesting an ectopic mediastinal parathyroid adenoma. The 4-mm adenoma was successfully removed through a mini-sternotomy incision using a gamma probe to identify the gland from the surrounding tissue. The patient made an uneventful recovery.Case Rep Oncol 2017;10:1105 –1111
Source: Case Reports in Oncology - Category: Cancer & Oncology Source Type: research
ConclusionsWhenever multiple osteolytic lesions are found in a patient without any known tumor, metabolic bone diseases including hyperparathyroidism should be highly considered.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Publication date: December 2017 Source:European Journal of Surgical Oncology, Volume 43, Issue 12 Author(s): Ioannis Christakis, Shahab Khan, Greg Sadler, Fergus Gleeson, Kevin Bradley, Radu Mihai
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
More News: Endocrinology | Hyperparathyroidism | PET Scan