Cell copying machine: How daughters look like their mothers

Tiny structures in our cells, called centrioles, control both cell division and motility. The number of these structures is highly monitored, with deviations causing infertility, microcephaly and cancer. A research team has uncovered the mechanism by which mother cells know that they provide the right number of centrioles to their daughters.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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CONCLUSION: Despite a more frequent presentation with advanced disease, colorectal cancer has a similar prognosis in pregnancy when compared with the general population. Diagnostic interventions and treatment should not be delayed due to the pregnancy but a balance between maternal and foetal wellbeing must always be kept in mind. PMID: 30010511 [PubMed - as supplied by publisher]
Source: Acta Chirurgica Belgica - Category: Surgery Tags: Acta Chir Belg Source Type: research
Publication date: Available online 11 July 2018Source: Mutation Research/Reviews in Mutation ResearchAuthor(s): Tahereh Setayesh, Armen Nersesyan, Miroslav Mišík, Franziska Ferk, Sabine Langie, Vanessa M. Andrade, Alexander Haslberger, Siegfried KnasmüllerAbstractHealth authorities are alarmed worldwide about the increase of obesity and overweight in the last decades which lead to adverse health effects including inflammation, cancer, accelerated aging and infertility. We evaluated the state of knowledge concerning the impact of elevated body mass on genomic instability. Results of investigations with hu...
Source: Mutation Research Reviews in Mutation Research - Category: Genetics & Stem Cells Source Type: research
Small higher risk of non-invasive breast and ovarian tumours may not be due to treatment Related items fromOnMedica Only a third of women with regular bloating would see their GP Infertility much more likely after childhood cancer Unprotected sex among British teens – soars Experts call for wider HPV vaccination Use of contraceptive pill may lead to longer life
Source: OnMedica Latest News - Category: UK Health Source Type: news
Authors: Anderson RC, Newton CL, Anderson RA, Millar RP Abstract The gonadotropin receptors, luteinising hormone receptor, and follicle-stimulating hormone receptor, play a central role in governing reproductive competency/fertility. Gonadotropin hormone analogues have been utilised clinically for decades, in assisted reproductive therapies, and in the treatment of various infertility disorders. While these treatments are effective, the clinical protocols demand multiple injections, and the hormone preparations can lack uniformity and stability. The past two decades have seen a drive to develop chimeric and modifie...
Source: Endocrine Reviews - Category: Endocrinology Tags: Endocr Rev Source Type: research
Publication date: Available online 28 June 2018Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Wanyuan Cui, Kelly-Anne PhillipsAbstractGlobally, breast cancer is the most common female reproductive cancer. Although not part of initial curative-intent treatment in women with other reproductive cancers, alkylating chemotherapy is often used to treat women with curable breast cancer. Chemotherapy-associated ovarian failure (COF) is a potential consequence of this treatment, and can cause infertility and increase the risk of cognitive impairment, cardiovascular disease and fractures from redu...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
Publication date: April 2018Source: Best Practice &Research Clinical Obstetrics &Gynaecology, Volume 48Author(s): Gabriela N. Algarroba, Joseph S. Sanfilippo, Hanna Valli-PulaskiAbstractThe 5-year survival rate for childhood cancer is over 80%, thereby increasing the number of young women facing infertility in the future because of the gonadotoxic effects of chemotherapy and radiation. The gonadotoxic effects of childhood cancer treatment vary by the radiation regimen and the chemotherapeutic drugs utilized. Although the American Society of Clinical Oncology guidelines recommend fertility preservation for all patie...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
In this study, we reported a comprehensive genome-wide DNA methylation landscape in chicken germ cells, and transcriptomic dynamics was also presented. By uncovering DNA methylation patterns on individual genes, some genes accurately modulated by DNA methylation were found to be associated with cancers and virus infection, e.g., AKT1 and CTNNB1. Chicken-unique markers were also discovered for identifying male germ cells. Importantly, integrated epigenetic mechanisms were explored during male germ cell differentiation, which provides deep insight into the epigenetic processes associated with male germ cell differentiation a...
Source: Stem Cell Reports - Category: Stem Cells Source Type: research
ConclusionIn cases of TML incidental finding by US with the presence of risk factors (personal history of testicular cancer, testicular atrophy, infertility, cryptorchidism) a consultation with a specialist should be considered. In the absence of risk factors, the occurrence of testicular cancer in patients with TML is similar to the risk of the general population.
Source: Basic and Clinical Andrology - Category: Urology & Nephrology Source Type: research
Fertility drugs don't increase a woman's chance of getting ovarian cancer, but infertility itself is associated with an increased risk, a new study suggests.
Source: WebMD Health - Category: Consumer Health News Source Type: news
FRIDAY, July 6, 2018 -- Fertility drugs do not increase a woman's risk of ovarian cancer, a new study suggests. It did find that infertility itself is associated with an increased risk of ovarian cancer. The researchers examined data from more than...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
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