Zika: Worse than we thought?

Follow me at @JohnRossMD Back in January, Dr. Anne Schuchat, Deputy Director of the Centers for Disease Control (CDC), didn’t seem all that worried about Zika. She expected it to cause only “very limited outbreaks” in the United States. Now, she’s not so sure. Last week, Dr. Schuchat admitted that Zika virus “seems to be a bit scarier than we initially thought.” Her unusual comments may be aimed partly at Congress, which has been reluctant to fund Zika control measures. But there are several reasons that public health officials are more nervous about Zika now than they were a few months ago. Our latest findings on Zika The evidence linking Zika infection in pregnancy and reduced fetal brain growth (microcephaly) has grown. Dr. Tom Frieden, director of the CDC, says that it is “now clear that the virus causes microcephaly.” In the laboratory, Zika virus can infect and kill developing nerve cells similar to those found in the fetal brain. Field studies in Brazil have confirmed a large spike in cases of microcephaly during the current Zika outbreak. The risk of microcephaly was increased five-fold in parts of Brazil with active Zika transmission, compared to areas where Zika was absent. In another Brazilian study, 29% of otherwise healthy pregnant women with Zika infection had an abnormal fetal ultrasound, with findings that included microcephaly, fetal growth restriction, and fetal death. These findings were not seen in pregnant w...
Source: New Harvard Health Information - Category: Consumer Health News Authors: Tags: Family Planning and Pregnancy Health Infectious diseases Prevention Travel health zika zika virus Source Type: news

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Publication date: Available online 16 January 2020Source: The Lancet HIVAuthor(s): Nicholas A Medland, Peter Banys, Van Phillip Baton, Johann Nadela, Lisa Maher, Ilya Tac-An
Source: The Lancet HIV - Category: Infectious Diseases Source Type: research
In 2019, 84% of Americans think vaccinating children is important, down from 94% in 2001; 10% still believe vaccines can cause autism, according to a new Gallup survey.Medscape Medical News
Source: Medscape Infectious Diseases Headlines - Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news
Conclusion Anlotinib effectively controlled the growth of NSCLC and improved TAO related symptoms. Anlotinib maybe normalize disordered growth of blood vessels through the VEGF signaling pathway, rather than simply inhibiting angiogenesis. 
 DOI: 10.3779/j.issn.1009-3419.2020.01.10
Source: Chinese Journal of Lung Cancer - Category: Cancer & Oncology Source Type: research
Infectious Bursal Disease (IBD) is an economically important irreversible immunosuppressive disease of young birds. The present study was designed to confirm the efficacy of two common diagnostic tests for the detection of Infectious Bursal Disease Virus (IBDV) from the three types of bursal samples collected from a recent outbreak in layer and broiler chickens of Gazipur district, Banglades...
Source: African Journal of Microbiology Research - Category: Microbiology Source Type: research
Publication date: Available online 15 January 2020Source: Journal of Theoretical BiologyAuthor(s): Sungwoo Ahn, Leonid L. RubchinskyAbstractThe mechanisms and properties of synchronization of oscillating ecological populations attract attention because it is a fairly common phenomenon and because spatial synchrony may elevate a risk of extinction and may lead to other environmental impacts. Conditions for stable synchronization in a system of linearly coupled predator-prey oscillators have been considered in the past. However, the spatial dispersion coupling may be relatively weak and may not necessarily lead to a stable, ...
Source: Journal of Theoretical Biology - Category: Biology Source Type: research
In this study, a hybrid model has been designed by using stacked generalisation ensemble technique for prediction of linear B-cell epitopes. The goal of using stacked generalisation ensemble approach is to refine predictions of base classifiers and to get rid of the worse predictions. In this study, six machine learning models are fused to predict variable length epitopes (6–49 mers). The proposed ensemble model achieves 76.6% accuracy and average accuracy of repeated 10-fold cross-validation is 73.14%. The trained ensemble model has been tested on the benchmark dataset and compared with existing sequential B-cell ep...
Source: IET Systems Biology - Category: Biology Source Type: research
We must work together to fight opioid abuse, a terrible condition that derails promising lives, contributes to our homelessness crisis and rips apart families and communities, say Dr. Lisa Egbert and Dr. Christopher Delecki.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
AbstractPurpose of ReviewPoint-of-care ultrasound (POCUS) has been widely adopted in the management of trauma patients by emergency and surgical specialists. Advances in technology, portability, and affordability have contributed to its exponential growth, particularly in the field of trauma anesthesia where ultrasound usage has steadfastly blossomed in recent years.Recent FindingsStudies and protocols have expanded beyond the oft-used focused assessment with sonography for trauma examination to include focused cardiac and lung examinations. POCUS may also be useful as an adjunct for airway management, vascular access, and...
Source: Current Anesthesiology Reports - Category: Anesthesiology Source Type: research
This article focuses on the most common devices along with their adoption and implementation into the practice of emergency medicine.Recent FindingsThe field of non-invasive neuromonitoring techniques is rapidly flourishing with an emphasis on portability and reproducibility, enhancing adoption into the practice of emergency medicine. Devices such as the extra-ventricular drain have proven to be of both diagnostic and therapeutic benefit, allowing for both global ICP monitoring and CSF sampling. However, as emergency physicians become more facile in the use of ultrasound, procedures such as optic nerve sheath diameter eval...
Source: Current Emergency and Hospital Medicine Reports - Category: Emergency Medicine Source Type: research
ConclusionThe results show excellent vessel patency and a good safety profile up to 1  year in the subgroup of Japanese patients in IMPERIAL treated with Eluvia for femoropopliteal artery disease.Level of EvidenceLevel 3; subgroup analysis of randomized trial.Clinical Trial RegistrationClinicalTrials.gov, identifier NCT02574481.
Source: CardioVascular and Interventional Radiology - Category: Radiology Source Type: research
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