Cell transplants to treat the “disease” of chronic pain

NIH Director's Wednesday Afternoon Lecture Series Neuropathic pain arises, in part, from a nerve injury-induced loss of spinal cord GABAergic inhibitory controls. Here we asked whether the neurological consequences of peripheral nerve damage can be overcome by transplanting embryonic cortical GABAergic precursor cells into the spinal cord. Using electrophysiological, neuroanatomical and behavioral approaches, we found that the cells integrate into host spinal cord circuits and can ameliorate the persistent pain and itch associated with nerve damage.For more information go to https://oir.nih.gov/walsAir date: 5/18/2016 3:00:00 PM
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