Mitochondrial dysfunction in inherited renal disease and acute kidney injury

Nature Reviews Nephrology 12, 267 (2016). doi:10.1038/nrneph.2015.214 Authors: Francesco Emma, Giovanni Montini, Samir M. Parikh & Leonardo Salviati Mitochondria are increasingly recognized as key players in genetic and acquired renal diseases. Most mitochondrial cytopathies that cause renal symptoms are characterized by tubular defects, but glomerular, tubulointerstitial and cystic diseases have also been described. For example, defects in coenzyme Q10 (CoQ10
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Review Source Type: research