Study: Chemo for Childhood Cancer Affects Male Survivors’ Fertility More Than Females’

By Stacy Simon RESOURCES: Preserving fertility in boys and teens with cancerPreserving fertility in girls and teens with cancer A study by researchers from leading cancer centers across the US has found that modern chemotherapy treatments have only a small impact on the ability of female childhood and adolescent cancer survivors to have children when they grow up. However, male survivors are more likely to have fertility problems. An estimated 400,000 survivors of childhood and adolescent cancer are living in the US today. However, therapies to treat their cancer can affect their reproductive health when they become adults, making it harder for them to have their own children. One way the medical community has responded to this problem is to lower the intensity of radiation treatments, and rely more on chemotherapy instead. Researchers from the Fred Hutchinson Cancer Research Center in Seattle and colleagues set out to study how much newer chemotherapy drugs affects childhood cancer survivors’ ability to have children. They looked at data from the Childhood Cancer Survivor Study, which tracks survivors of childhood cancer who were treated in the US and Canada between 1970 and 1999. The study looked at 10,938 childhood cancer survivors who were treated with 14 different commonly prescribed chemotherapy drugs and compared the number of pregnancies and children they eventually had with 3,949 of their brothers and sisters. The study focused on survivors who were treat...
Source: American Cancer Society :: News and Features - Category: Cancer & Oncology Tags: Cancer in Adolescents Childhood Cancer Source Type: news

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Discussion" sections of this study and the following article published in Lung Cancer: "CYP2E1 Rsa I/Pst I polymorphism is associated with lung cancer risk among Asians" by Ping Zhan, Jing Wang, Yu Zhang, Li-Xin Qiu, Su-feng Zhao, Qian Qian, Shu-Zhen Wei, Li-Ke Yu and Yong Song, Volume 69, 2010, pages 19-25. REFERENCE Shen Z-T, Wu X-H, Li B, Shen J-S, Wang Z, Li J, Zhu X-X. CYP2E1 Rsa Ι/Pst Ι polymorphism and lung cancer susceptibility: a meta-analysis involving 10,947 subjects. J Cell Mol Med. 2015;19:2136-2142. https://doi.org/10.1111/jcmm.12579. PMID: 29924497 [PubMed - in process]
Source: J Cell Mol Med - Category: Molecular Biology Authors: Tags: J Cell Mol Med Source Type: research
Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print
Source: Journal of Pediatric Endocrinology and Metabolism - Category: Endocrinology Source Type: research
CONCLUSION: First line management of infertility once a diagnosis of PCOS is made should include weight loss and exercise with goals to below class 2 obesity (BMI
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
CONCLUSION: There was a trend towards an increase in latency interval between cases of PV-PROM managed by SR and expectant management in our institution. When combined with the existing literature data, there may be an improvement in latency. PMID: 29921428 [PubMed - in process]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
Authors: Lam TH, Wong KH, Chan KK, Chan MC, Chao DV, Cheung AN, Fan CY, Ho J, Hui EP, Lam KO, Law CK, Law WL, Loong HH, Ngan RK, Tsang TH, Wong MC, Yeung RM, Ying AC, Ching R Abstract In Hong Kong, breast cancer is the most common cancer among women and poses a significant health care burden. The Cancer Expert Working Group on Cancer Prevention and Screening (CEWG) was set up in 2002 by the Cancer Coordinating Committee to review and assess local and international scientific evidence, and to formulate recommendations for cancer prevention and screening. After considering the local epidemiology, emerging scientific ...
Source: Hong Kong Medical Journal - Category: General Medicine Tags: Hong Kong Med J Source Type: research
Authors: Chow LC PMID: 29926791 [PubMed - in process]
Source: Hong Kong Medical Journal - Category: General Medicine Tags: Hong Kong Med J Source Type: research
By SAURABH JHA Though the exact cost of Modicare, the government’s extension of health insurance for poor people, estimated at one lakh crore (a trillion U.S. dollars), is open for debate, what is not disputable is that the cost of insuring India’s poor won’t fall with time. A sure way of accelerating healthcare inflation, that is speeding the rate of increase of healthcare costs, is by subsidizing or paying for health insurance. Insurance is like Newton’s Second Law of Motion – the velocity keeps increasing as long as the force is applied. Healthcare is a peculiar industry. Cars get cheaper b...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: OP-ED Source Type: blogs
LIVER cancer symptoms are often vague and difficult to spot, but can include weight loss and vomiting. These are the warning signs of the rare cancer - are you at risk of the deadly disease?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Pham T, Bajaj A, Berberi L, Hu C, Taleban S Abstract Background/Aims: To determine the accuracy of identifying ≥6-mm adenomatous polyps during colonoscopy and define its impact on subsequent interval screening. Methods: We conducted a retrospective study of patients who underwent colonoscopies at Banner University Medical Center, Tucson from 2011 to 2015. All patients with ≥6-mm adenomatous polyps based on their colonoscopy report were included. Adenomatous polyps were excluded if they did not meet the criteria. Discrepancies in the polyp size were determined by calculating the percentage of size...
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research
CONCLUSIONS: Results suggest that the over-expression of p16 seen in LP play a part in the histopathology of the disease. PMID: 29924765 [PubMed - as supplied by publisher]
Source: Medicina Oral, Patologia Oral y Cirugia Bucal - Category: ENT & OMF Tags: Med Oral Patol Oral Cir Bucal Source Type: research
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