cGAS-STING do it again: pivotal role in RNase H2 genetic disease

RNase H2 is a susceptibility gene for the Aicardi–Goutières syndrome (AGS), a genetic auto-inflammatory disease. Mackenzie and colleagues now report a tractable mouse model for the disease, implicating the cGAS-STING pathway.
Source: EMBO Journal - Category: Molecular Biology Authors: Tags: Immunology News [amp ] Views Source Type: research