Pro-oxidant Activity and Genotoxicity of the Astronium fraxinifolium Using Wing SMART and Allium cepa Test

Astronium fraxinifolium is an arboreal species found throughout the Brazilian Cerrado region and used in folk medicine as antimicrobial, anti-hemorrhagic and healing. Pro-oxidant activity of extracts of A. fraxinifolium through Relative Electrophoresis Mobility (REM) of Bovine Serum Albumin (BSA) protein in presence of the extract and Cu2+ and also the genotoxic potential through Somatic Mutation and Recombination Test (SMART) and Allium cepa tests has been investigated during this study. In the REM, the extracts acting exclusively on BSA resulted in a band formation with higher molecular weight than BSA, probably due to oxidative action of the extracts. In presence of Cu2+ and extracts occurred protein fragmentation due to Cu2+ oxidative action potentiated by the extracts. In SMART test the frequency of mutant spots increases with the increased concentration of extract A. fraxinifolium (50 mg mL–1 = 1.40 and 100 mg mL–1 = 2.66). The HB cross shows a decrease in the total of mutant spots frequency for the different treatments (50 mg mL–1 = 6.60 and 100 mg mL–1 = 3.25). Evaluation of A. cepa test demonstrated the following results (concentration extract = chromosomal abnormalities) 1 mg mL–1 = 85, 10 mg L–1 = 61 50 mg mL–1 = 53, 100 mg mL–1 =33 and MMS 10 mg L–1 = 50. Genotoxic and cytotoxic actions can be explained by the actions of tannins present in its composition. But there may be other substances that also act for such results...
Source: Research Journal of Medicinal Plant - Category: Complementary Medicine Source Type: research

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Publication date: Available online 8 December 2018Source: Journal of Sound and VibrationAuthor(s): Andrè M.N. Spillere, Julio A. CordioliAbstractAcoustic liners are widely employed in turbofan aero-engines as acoustic treatment. Their performance is determined by its acoustic impedance in the presence of flow. In recent years, much effort has been devoted to find the “optimum impedance” i.e. the impedance that results in the maximum attenuation. Although such analysis can be carried out by means of numerical simulations, analytical expressions can also be derived in order to predict the optimum impedance...
Source: Journal of Sound and Vibration - Category: Physics Source Type: research
Publication date: Available online 8 December 2018Source: Journal of Sound and VibrationAuthor(s): Xiaoling Jin, Huang Xu, Yong Wang, Zhilong HuangAbstractAs a mechanical system is placed on a belt moving with a constant speed, the friction between the mass block and the belt induces the stick-slip vibration. If the mechanical system is imposed by random external excitations at the same time, it will suffer from more complex random stick-slip vibration which is quite difficult to predict analytically. This manuscript tries to establish an approximately analytical procedure to evaluate the response statistics of the random ...
Source: Journal of Sound and Vibration - Category: Physics Source Type: research
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Source: Progres en Urologie - Category: Urology & Nephrology Tags: Prog Urol Source Type: research
Authors: Ortiz A, Sanchez-Niño MD, Crespo-Barrio M, De-Sequera-Ortiz P, Fernández-Giráldez E, García-Maset R, Macía-Heras M, Pérez-Fontán M, Rodríguez-Portillo M, Salgueira-Lazo M, Sánchez-Álvarez E, Santamaría-Olmo R, Simal-Blanco F, Pino-Pino MD Abstract The Global Burden of Disease (GBD) study measures the health of populations worldwide and by country on an annual basis and aims at helping guide public policy on health issues. The GBD estimates for Spain in 2016 and recent trends in mortality and morbidity from 2006 to 2016 were recent...
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - Category: Urology & Nephrology Tags: Nefrologia Source Type: research
Authors: Rodríguez-Sánchez E, Navarro-García JA, Aceves-Ripoll J, Álvarez-Llamas G, Segura J, Barderas MG, Ruilope LM, Ruiz-Hurtado G Abstract BACKGROUND AND OBJECTIVE: Matrix metalloproteinases (MMPs) are involved in deleterious tissue remodeling associated with target organ damage in renal disease. The aim of this study was to study the association between renal dysfunction and activity of the inflammatory metalloproteinase MMP-9 in hypertensive patients with mild-moderate chronic kidney disease (CKD). MATERIAL AND METHODS: Plasmatic active MMP-9, total MMP-9, tissue inhibitor of M...
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - Category: Urology & Nephrology Tags: Nefrologia Source Type: research
BED BUG bites causes irritation. If you have an infestation of bed bugs your are likely to be bitten. How do you spot the bites? How to get rid of bed bugs. Pictures of bites.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 8 December 2018Source: Biocatalysis and Agricultural BiotechnologyAuthor(s): Kandasamy Kathiresan, Rajendran Narendran, Kaliyamoorthy Kalidasan, Palanisamy DineshAbstractIn this paper, we analyzed the growth performance of 3 year old Rhizophora mucronata in response to pruning of shoot branches in the lower trunk, on 70, 117, 180 and 292 days of the experiment corresponding to four seasons (Post monsoon, summer, Pre monsoon and monsoon). The growth increased with number of shoot branch pruned, and days of growth. The pruning exercise exhibited significant promontory effect on the leaf exp...
Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
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Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
Publication date: Available online 8 December 2018Source: Journal of Molecular StructureAuthor(s): C. Jellali, N. Dridi, N. Maaroufi, F. Kwabia Tchana, Xavier Landsheere, H. ArouiAbstractUsing Fourier transform spectrometer, He-broadening coefficients have been measured for the first time in the P and R branches of the 2ν1 parallel band of carbonyl sulfide (OCS). The measurements have been performed at room temperature for rotational quantum number up to J = 70. A total of 131 lines were measured using a nonlinear least squares multi-pressure spectrum fitting procedure. Since the measurements have been performed usi...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
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