Cytotoxicity, Genotoxicity and Antioxidant Activity of Extracts from Capsicum spp.

Extracts of different genotypes of Capsicum (C. annuum L., C. baccatum L., C. chinense Jacq., C. frutescens L. and C. praetermissum) were investigated for total phenolics, flavonoids, capsaicinoids contents and antioxidant activity objectifying to determine the relations between these bioactive compounds and the antioxidant capacity and also examine its cytotoxic and genotoxic potential. Capsicum praetermissum showed the highest total antioxidant activity and the highest concentrations of phenolic compounds and flavonoids. For C. annuum and C. frutescens the antioxidant activity was significant and the levels of phenolic compounds and flavonoids intermediate, while C. baccatum demonstrated the lowest antioxidant activity independent of significant levels of these compounds. Capsicum chinense showed the lowest level of total phenols and flavonoids despite expressive antioxidant activity. The determination of capsaicinoid content revealed higher levels of capsaicin and dihydrocapsaicin for extracts of C. praetermissum, intermediate levels to C. baccatum, C. chinense and C. frutescens, whereas, the C. annuum showed the lowest levels of capsaicinoids, typical of these ornamental genotype. The extracts of C. praetermissum and C. baccatum exhibited low cytotoxic potential compared to other genotypes. The genotoxic potential was variable between analyzed genotypes, with C. praetermissum presenting the lowest rates. All species showed a dose-effect relationship dependent of extract c...
Source: Research Journal of Medicinal Plant - Category: Complementary Medicine Source Type: research

Related Links:

Date: Tuesday, 06 19, 2018; Speaker: Lewis Kay, Professor, University of Toronto; Building: Building 5; Room 127
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Thursday, 06 21, 2018; Speaker: No speaker for this event; Building: Building 31
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Wednesday, 06 27, 2018; Speaker: Eric Alani, Ph.D., Professor, Cornell University; Building: Building 37; Conference Room 6041/6107
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Wednesday, 09 26, 2018; Speaker: Marie Caudill, Stephen H. Weiss Presidential Fellow and Professor, Dividion of Nutritional Sciences, Cornell University; 6100 Executive Blvd; 1A01
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Wednesday, 10 10, 2018; Speaker: Cynthia V. Rider, Ph.D, National Toxicology Program, National Institute for Environment Health; 6100 Executive Blvd; 1A01
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Wednesday, 11 07, 2018; Speaker: Carrie Finno, DVM, Ph.D.---Director, , UC Davis School of Veterinary; 6100 Executive Blvd; 1A01
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Wednesday, 12 12, 2018; Speaker: Orlando Gutierrez, M.D., M.M.Sc., University of Alabama at Birmingham; 6100 Executive Blvd; 1A01
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Wednesday, 02 06, 2019; Speaker: Connie M. Weaver, Ph.D., R.D.--Professor, Department of Nutrition, Purdue University; 6100 Executive Blvd; 1A01
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Wednesday, 03 27, 2019; Speaker: Dennis M. Bier, M.D. USDA/Agricultural Research Service, Baylor College of Medicine; 6100 Executive Blvd; 1A01
Source: NIH Calendar of Events - Category: American Health Source Type: events
Date: Wednesday, 04 10, 2019; Speaker: JoAnn Manson, M.D., M. Ph., Dr. Ph--Professor, Harvard T.H, Chan School of Public Health; 6100 Executive Blvd; 1A01
Source: NIH Calendar of Events - Category: American Health Source Type: events
More News: Complementary Medicine | Health | Herbs | Nutrition | Peppers | Study