GSE80263 A Unique Rearrangement of PDGFRα and ETV6 in a new t(4;12;6) in a Patient with Acute Myeloid Leukemia (M4) Progressed from Chronic Myelomonocytic Leukemia.

Conclusion: This is the first report of development of a variant t(4;12;6) and fusion PDGFRα/ETV6 fusion that developed during transition from CMML to AML. Despite PDGFRα/ETV6 fusion the patient did not respond to imatinib.

http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE80263

Source: GEO: Gene Expression Omnibus - April 15, 2016 Category: Genetics & Stem Cells Tags: Genome variation profiling by array Homo sapiens Source Type: research