Regulation of IgA Class Switch Recombination in Immunoglobulin A Nephropathy: Retinoic Acid Signaling and BATF.

CONCLUSION: These data point toward the role of RA signaling together with BATF in IgA CSR of IgAN, and the data also support the notion that mucosal immunization with neoantigen results in impaired mucosal and systemic IgA responses.
PMID: 27073891 [PubMed - as supplied by publisher]

Source: American Journal of Nephrology - April 13, 2016 Category: Urology & Nephrology Authors: He L, Peng X, Chen Y, Liu G, Liu Z, Zhu J, Liu Y, Liu H, Liang Y, Liu F, Sun L, Peng Y Tags: Am J Nephrol Source Type: research