The Zika Virus Lesson? A New Approach Is Needed to Combat Pandemics

The Zika virus attracted many headlines this winter, but a recent admission by the chief medical officer at a leading vaccine manufacturer -- that the world is ill-prepared to deal with pandemic outbreaks -- underscores a fundamental problem. To ensure safety and efficacy, the federal government's regulatory approval process for new vaccines may extend development timelines for years. So when The New York Times reports that "eighteen organizations are working on developing a vaccine for the Zika virus," it is likely that those companies will labor for a very long time. Vaccinations rightly require strict federal approval processes to ensure the safety and the efficacy of a new vaccination. But when pandemic viruses like Zika spread quickly and unexpectedly, the world realizes there is little that can practically and immediately be done other than to implement strict infection control measures up to and including quarantines. This has been true for prior pandemics such as the swine flu, avian flu, SARS and Ebola. That reality speaks to the need for a new approach to pandemic viruses, including influenza. The good news with Zika is that it is a fairly stable virus, unlike other frequently mutating viruses such as the influenza virus. During the Zika epidemic in Brazil, reported microcephaly cases rocketed to 2,700 in 2015 and at least 40 babies died. By comparison, there were only 147 reported microcephaly cases in Brazil altogether in 2014. In 60 to 80 pe...
Source: Science - The Huffington Post - Category: Science Source Type: news

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HIGH blood pressure symptoms include chest pain, shortness of breath, and finding blood in your urine. But you could be at risk of “life-threatening” hypertension if your headache is accompanied by these signs.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
CONCLUSION: Primary care physicians play a key role in vaccination. The focus of further strategies should lie above all in improved patient education and in targeted reminders for patients who neglect to vaccinate themselves and/or their children. PMID: 30518471 [PubMed - in process]
Source: Deutsches Arzteblatt International - Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
Conclusion: We have developed and validated a clinical prediction model that can be used to identify patients at high risk of a poor outcome after TKA. This clinical risk score may be an aid to shared decision-making between patient and clinician. PMID: 30506023 [PubMed]
Source: Adv Data - Category: Epidemiology Authors: Tags: Rheumatol Adv Pract Source Type: research
CONCLUSION: Our first results confirm that the FMT seems to be safe, with an impact on VRE colonization over time that may help control outbreaks. PMID: 30502308 [PubMed - as supplied by publisher]
Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
This study evaluated associations between psychosocial variables and 6-Minute Walk Distance (6MWD) to identify factors that motivate walking. 142 Individuals with IC (116 males, mean 66.9y [SD=10.2]) completed cross-sectional assessments of sociodemographics, walking treatment beliefs and intention (Theory of Planned Behaviour [TPB]), illness perceptions (Revised Illness Perceptions Questionnaire), and 6MWD. Multiple linear regression evaluated relationships between treatment beliefs (block 1) and illness perceptions (block 2) with intention and 6MWD. TPB constructs were associated with intention (R=.72, p
Source: Journal of Aging and Physical Activity - Category: Geriatrics Tags: J Aging Phys Act Source Type: research
CONCLUSION: On the basis of this preliminary study, it appears that the use of a barrier membrane to cover the lateral bone window during maxillary sinus floor augmentation surgery with a lateral approach reduces the postoperative dislodgement of the bone graft throughout the sinus antrostomy and prevents the bone substitute particles penetrating within the buccal mucosa, which is related to postoperative morbidity. PMID: 30521657 [PubMed - as supplied by publisher]
Source: International Journal of Oral and Maxillofacial Implants - Category: ENT & OMF Tags: Int J Oral Maxillofac Implants Source Type: research
The American scientist, whose new book explains why vaccines didn ’t cause his daughter’s autism, on why conspiracy theorists need to be challengedPeter Hotez is dean of the National School of Tropical Medicine at Baylor College of Medicine in Houston, Texas. He has worked on developing vaccines for hookworm andschistosomiasis, and is a vocal opponent of the anti-vaccine movement. His daughter Rachel is autistic and he has written a book,Vaccines Did Not Cause Rachel ’s Autism, in which he describes her illness and tackles the newly resurgent anti-vaccine movement.Why did you decide to write this book thr...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Vaccines and immunisation Science Autism Andrew Wakefield Source Type: news
ConclusionElderly patients who suffer a ground-level fall do not benefit from PAN-SCAN, even when presenting with rib, thoracolumbar, and/or pelvic fractures.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
“It is borderline genocide,” said DeLuca, 37. “You are allowing [chronic pain patients] to go home and essentially suffer until they kill themselves.” Last year, Lauren DeLuca went to the emergency room in the middle of the night, violently ill and in pain with a pancreatic attack. Despite the fact that she was passing out and vomiting profusely, DeLuca said that she received little help. “I was essentially turned away,” she told The Fix. “Everywhere [I went] I was being accused of lying, accused of making it up.” Over the next three weeks, DeLuca lost 20 pounds, unable to ea...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Disorders Health-related Medications Publishers Substance Abuse The Fix Chronic Pain opioid addiction Opioids Source Type: blogs
This article will review the injection therapies which are frequently used in elite sports injury management and describe other less commonly used injection therapies that are available to the treating clinician and athlete. The evidence base, where available, for each treatment option will be summarised.
Source: European Journal of Radiology - Category: Radiology Source Type: research
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