The Zika Virus Lesson? A New Approach Is Needed to Combat Pandemics

The Zika virus attracted many headlines this winter, but a recent admission by the chief medical officer at a leading vaccine manufacturer -- that the world is ill-prepared to deal with pandemic outbreaks -- underscores a fundamental problem. To ensure safety and efficacy, the federal government's regulatory approval process for new vaccines may extend development timelines for years. So when The New York Times reports that "eighteen organizations are working on developing a vaccine for the Zika virus," it is likely that those companies will labor for a very long time. Vaccinations rightly require strict federal approval processes to ensure the safety and the efficacy of a new vaccination. But when pandemic viruses like Zika spread quickly and unexpectedly, the world realizes there is little that can practically and immediately be done other than to implement strict infection control measures up to and including quarantines. This has been true for prior pandemics such as the swine flu, avian flu, SARS and Ebola. That reality speaks to the need for a new approach to pandemic viruses, including influenza. The good news with Zika is that it is a fairly stable virus, unlike other frequently mutating viruses such as the influenza virus. During the Zika epidemic in Brazil, reported microcephaly cases rocketed to 2,700 in 2015 and at least 40 babies died. By comparison, there were only 147 reported microcephaly cases in Brazil altogether in 2014. In 60 to 80 pe...
Source: Science - The Huffington Post - Category: Science Source Type: news

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LUNG cancer symptoms include a cough the won ’t go away, unexplained weight loss and severe chest pain. But you could also be at risk of deadly lung tumour signs if your eyes are a distinctive colour.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Luo TD, Marois AJ, Smith TL, Willey JS, Emory CL Abstract Ascorbic acid (vitamin C) is an essential micronutrient with evidence supporting its role in bone formation, tissue repair, and collagen production. Its clinical importance to the field of orthopaedic surgery has yet to be fully defined. Several observational studies have shown improved bone density and reduced hip fracture risk with supplementation. Its effect on bone fracture and soft tissue injury has been promising in animal models, but is not adequately studied in human trials. Results have been mixed concerning its role in chondroprotection an...
Source: Journal of surgical orthopaedic advances - Category: Orthopaedics Tags: J Surg Orthop Adv Source Type: research
China has confirmed a new outbreak of African swine fever in Yunnan province, authorities said on Thursday, as the highly contagious disease spreads through the world's largest hog herd.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
ConclusionsThis single-dose study found that the test product (RB naproxen sodium tablets) and reference product (Aleve naproxen sodium tablets) met the regulatory criteria for bioequivalence in these fasted male and female volunteers; both test and reference products were found to be safe and well tolerated.Graphical Abstract
Source: Current Therapeutic Research - Category: Drugs & Pharmacology Source Type: research
A new study from the CDC found cases of women positive for HPV types 16 and 18 - responsible for about 70% of cervical cancers worldwide - fell by more than 30% from 2008 to 2014.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
(American Association for Cancer Research) An analysis of cervical precancers over a period of seven years showed that two strains of human papillomavirus (HPV) that have been targeted by vaccination since 2006 have declined, accounting for a smaller proportion of cervical disease. The study offers evidence that HPV vaccination reduced the incidence of infections that can lead to cervical cancer.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
Analyst, 2019, Accepted Manuscript DOI: 10.1039/C8AN02295J, MinireviewHanbi Kim, Doo-Ryeon Chung, Minhee Kang Infectious diseases are transmissible or communicable illnesses and can spread quickly in some areas and become epidemics. It is critical to quickly diagnose initial infections and prevent further spread through... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
The authors present an unusual series of patients with complaints of persistent suprapubic pain. The report details their presumptive explanation for the etiology of the discomfort and a successful treatment regimen. This observation gives urologists a reasonable plan for management of symptomatic suprapubic fluid collections in males with a history of bladder exstrophy and/or epispadias repair.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
We describe a novel technique of flexor carpi radialis (FCR) tendon interposition to tackle this condition. Our common treatment for CMC arthritis is trapezium resection with ligament reconstruction and tendon interposition with half of the FCR. With this procedure, through the same exposure, the proximal part of the trapezoid is resected. An anchor is placed into the trapezoid and the sutures are passed through a remnant of the FCR. Thus the FCR is pulled in between the scaphoid and the trapezoid and secured in place. We performed this procedure in 13 hands with average follow-up of 36 months. All patients were satisfied ...
Source: Techniques in Hand and Upper Extremity Surgery - Category: Surgery Tags: Techniques Source Type: research
In this retrospective study, we report the preliminary results of a novel technique for volar vascularized strut grafting to treat avascular scaphoid nonunion by using the 1,2 intercompartmental supraretinacular artery through a single incision. Forty-three of 45 patients with avascular scaphoid nonunion healed at a mean of 13 weeks (range, 3 to 10 mo). Complications consisted of 1 pin tract infection that resolved with oral antibiotics and 4 cases of transient dysesthesia of the radial sensory nerve. In 4 patients with equivocal radiographs, computed tomography scans confirmed bony union. The 2 patients who remaine...
Source: Techniques in Hand and Upper Extremity Surgery - Category: Surgery Tags: Techniques Source Type: research
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