Proton Therapy in Children: A Systematic Review of Clinical Effectiveness in 15 Pediatric Cancers

Because it spares many normal tissues and reduces the integral dose, proton therapy (PT) is the preferred tumor irradiation technique for treating childhood cancer. However, to the best of our knowledge, no systematic review of the clinical effectiveness of PT in children has been reported in the scientific literature. A systematic search for clinical outcome studies on PT published between 2007 and 2015 was performed in Medline (through OVID), EMBASE, and the Cochrane Library. Twenty-three primary studies were identified, including approximately 650 patients overall.

Source: International Journal of Radiation Oncology * Biology * Physics - October 17, 2015 Category: Radiology Authors: Roos Leroy, Nadia Benahmed, Frank Hulstaert, Nancy Van Damme, Dirk De Ruysscher Tags: Pediatrics Source Type: research