Rosiglitazone is a superior bronchodilator compared to chloroquine and beta-adrenoceptor agonists in mouse lung slices

Conclusions: This study demonstrates the superior effectiveness of RGZ in comparison to CQ and beta-adrenoceptor agonists as a dilator of mouse small airways. Further investigation of the mechanisms underlying the relatively greater efficacy of RGZ under these conditions are warranted and should be extended to include studies in human asthmatic airways.

http://respiratory-research.com/content/15/1/29

Source: Respiratory Research - March 12, 2014 Category: Respiratory Medicine Authors: Chantal DonovanMirjam SimoonsJames EspositoJean Ni CheongMeaghan FitzPatrickJane Bourke Source Type: research