Carcinomatous Meningitis Due to Metastatic Linitis Plastica (P4.235)

Conclusions: There are few reports of carcinomatous meningitis from linitis plastica. This may be due to a high early mortality rate, before malignant cells can reach the CNS. We suggest that patients with a history of gastric adenocarcinoma presenting with CNS complaints warrant an initial work-up with brain imaging, where findings of cranial nerve enhancement should increase suspicion for CM, and LP, focused on cytology. Unfortunately, CM in the setting of gastric adenocarcinoma has an overall poor prognosis.Disclosure: Dr. Narula has nothing to disclose. Dr. Masangkay has nothing to disclose.
Source: Neurology - Category: Neurology Authors: Tags: Neuro-oncology: Neurologic Complications of Cancer Source Type: research