Modifications to bicarbonate conductivity: A way to increase phosphate removal during hemodialysis? Proof of concept

Discussion The decrease of in‐session phosphate and the increase in KM reflect phosphate refilling during hemodialysis. Thus, modulation of serum bicarbonate may play a role in controlling the phosphate pool. Even though correcting metabolic acidosis during hemodialysis remains important, alkaline excess can impair phosphate mobilization clearance. Clinical trials are needed to test the efficiency and relevance of a strategy where bicarbonatemia is corrected less at the beginning of sessions.
Source: Hemodialysis International - Category: Hematology Authors: Tags: Original Article Source Type: research