4 Advances That Make In Vitro Fertilization More Successful Than Ever

Tanmoy Mukherjee, MD Associate Director, Division of Reproductive Endocrinology and Infertility, Mount Sinai Health System; Co-Director, Reproductive Medicine Associates of New York; Assistant Clinical Professor of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai When prospective parents who are unable to conceive a child on their own consult me for assistance, I am excited to help them build their families. But for them, dealing with the challenges of infertility can be as stressful as having cancer. Fortunately, the latest advances in in vitro fertilization (IVF) are giving them a better chance than ever of achieving their dreams. What Is In Vitro Fertilization? IVF is a medical and surgical approach to conception that involves fertilizing eggs outside a woman's body. Normally, women produce one egg per monthly menstrual cycle, but IVF requires several eggs to increase the effectiveness of each procedure. To boost egg production, women take a series of medications over the course of two weeks. Mature eggs are then retrieved during a minor surgical procedure in a physician's office, and fertilized in the laboratory with the partner's sperm. After about five days, one or two of the developing embryos are inserted into the woman's uterus or, more and more these days, biopsied, frozen, and saved for future use. IVF treats infertility caused by various factors, including damaged or blocked fallopian tubes, male problems (such as low or n...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Publication date: Available online 16 November 2018Source: Seminars in Cancer BiologyAuthor(s): Besa Xhabija, Benjamin L. KidderAbstractEpigenetic regulation of chromatin plays a critical role in controlling stem cell function and tumorigenesis. The histone lysine demethylase, KDM5B, which catalyzes the demethylation of histone 3 lysine 4 (H3K4), is important for embryonic stem (ES) cell differentiation, and is a critical regulator of the H3K4-methylome during early mouse embryonic pre-implantation stage development. KDM5B is also overexpressed, amplified, or mutated in many cancer types. In cancer cells, KDM5B regulates e...
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 16 November 2018Source: Cancer GeneticsAuthor(s): Jennelle C. Hodge, David Bosler, Lauren Rubinstein, Navid Sadri, Shashirekha ShettyAbstractThe inv(3)(q21q26.2) altering a single chromosome 3 homolog is an established myeloid malignancy-associated entity. Comparatively, double inv(3) cases involving both homologs are exceedingly rare with 13 reports across AML, CML and MDS. This scarcity was confirmed by finding only 2 new cases out of 34,898 bone marrows collected during a 55 year period at a large medical center (0.0005%). The double inv(3) was detected by karyotype and confirmed by FI...
Source: Cancer Genetics - Category: Cancer & Oncology Source Type: research
New research published inNeuro-Oncology examines the controversial link between intracranial volume and high-grade glioma.
Source: CancerNetwork - Category: Cancer & Oncology Authors: Source Type: news
Date: Friday, 11 16, 2018; Speaker: Dr. Anne Steiner, Professor and Chief, Division of Reproductive Endocrinology and Infertility (REI, Duke University; Building: Building 10 (Clinical Center); FAES 6&7
Source: NIH Calendar of Events - Category: American Health Source Type: events
Publication date: Available online 15 November 2018Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)Author(s): Funda Üstün, Burcu Tokuc, Ebru Tastekin, Gülay DurmuĊŸ AltunAbstractAimIn lung cancer, axillary lymph node metastases (ALM) are rare, and according to the 8th grading system, it is classified as M1b disease. The aim of this study is to evaluate (i) the presence of ALM, and (ii) the effect of the primary tumors characteristics on the development of ALM.MethodsWe performed a descriptive cross-sectional study, with retrospective revision, to identify ALM.ResultsTh...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - Category: Nuclear Medicine Source Type: research
Authors: Gong W, Qi X Abstract Frailty is characterized by a state of vulnerability to poor resolution of homoeostasis after a stressor event and is a consequence of age-related decline in many physiological systems during a lifetime. To access the association between frailty and delayed recovery of gastrointestinal function in patients undergoing elective colorectal cancer resections, 241 patients who had undergone elective colorectal cancer resections from July 2015 to August 2017 were investigated. The association of frailty with delayed recovery of gastrointestinal function, length of stay (LOS), and whether or...
Source: Journal of Investigative Surgery - Category: Surgery Tags: J Invest Surg Source Type: research
CONCLUSIONS: Endobronchial targeting of peripheral airway targets is feasible using existing open-source technology. Notwithstanding the shortcomings of current commercial platforms, technological improvements in EM tracking and registration accuracy fostered by open-source technology may provide the impetus for widespread clinical uptake of electromagnetic navigation in bronchoscopy. PMID: 30428748 [PubMed - as supplied by publisher]
Source: Minimally Invasive Therapy and Allied Technologies - Category: Surgery Tags: Minim Invasive Ther Allied Technol Source Type: research
Linda Woolley, 73, was diagnosed with 'likely' kidney cancer at the University of Colorado Hospital in March. She had both organs removed before doctors realized she was cancer-free.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
CONCLUSIONS: HS-FCM can sensitively detect minor PNH clones and reduce false-positive C-FCM minor PNH clone cases in AA/low-grade MDS patients. PMID: 30430777 [PubMed - in process]
Source: Annals of Laboratory Medicine - Category: Laboratory Medicine Tags: Ann Lab Med Source Type: research
Authors: Lerner AD, Feller-Kopman D PMID: 30433839 [PubMed - as supplied by publisher]
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research
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