For treating a leading cause of osteoporosis, surgery is better than widely used medications

While most cases of osteoporosis are caused by normal aging, another leading cause of the bone-loss disease is a condition called hyperparathyroidism, in which the parathyroid glands release an excessive amount of a hormone that regulates the body’s calcium levels. Doctors commonly treat hyperparathyroidism using a class of prescription drugs called bisphosphonates, including alendronate (marketed under the brand name Fosamax) and ibandronate (Boniva), which are supposed to strengthen bones. Now, a study led by scientists at UCLA found that those drugs actually increase the risk of fracture, meaning that taking them is worse than doing nothing at all to treat the condition. The research also revealed that patients who have surgery to remove the overactive parathyroid glands have fewer subsequent bone fractures. The report appears in the April 5 issue of the Annals of Internal Medicine. About 400,000 people in the U.S. — 1 in 400 women and 1 in 1,200 men — have hyperparathyroidism; and osteoporotic fractures are a major public health and economic burden, said Dr. Michael Yeh, an associate professor of surgery and medicine, and the study’s first author. “Hip fractures in particular are associated with significant rates of mortality, disability and loss of independence,” said Yeh, who also is the chief of endocrine surgery at the UCLA David Geffen School of Medicine. “Before this study, there was no data that compared parathyroid surgery...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news

Related Links:

We describe the components of a CLSM system and assess how modern implementations of the approach have further expanded the use of the technique. Finally, we briefly outline some practical considerations to take into account when acquiring data using a CLSM system. © 2018 by John Wiley &Sons, Inc. PMID: 29927100 [PubMed - as supplied by publisher]
Source: Current Protocols in Cytometry - Category: Molecular Biology Tags: Curr Protoc Cytom Source Type: research
Laura Mosqueda, a geriatrician, wants to train new doctors to better care for elderly people as the country ’ s population ages. She will face a big challenge as USC reels from drug and sexual misconduct scandals that have enraged students and landed the university in legal hot water.Kaiser Health News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news
An author of 15 books, Ms. King founded a summer camp and school to help children with learning disabilities that had often gone undiagnosed.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Dyslexia Deaths (Obituaries) King, Diana Hanbury The Kildonan School Source Type: news
Authors: Russo L, Craig F, Ruggiero M, Mancuso C, Galluzzi R, Lorenzo A, Fanizza I, Trabacca A Abstract INTRODUCTION: Recent evidence suggests that impairments in social cognition are associated to the cognitive abilities needed to take several viewpoints in perceptual situations and body awareness. The aim of the current study was to investigate Visual Perspective Taking (VPT) and Body awareness performance in a group of children with Autism Spectrum Disorders (ASD) compared with a group of children with Intellectual Disability (ID) and typically developing (TD) children. METHODS: Our groups were administered ...
Source: Cognitive Neuropsychiatry - Category: Psychiatry Tags: Cogn Neuropsychiatry Source Type: research
He helped develop two technologies that allowed people who could not use a mouse to communicate with a computer, and thus with the world.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Gips, James E (1946-2018) Deaths (Obituaries) Disabilities Computers and the Internet Boston College Science and Technology Source Type: news
Purpose: To investigate the relationship of the pre–anti-vascular endothelial growth factor (VEGF) retinal tissue area (RTA) and optical density (ODRT) of the retinal optical slice portion located in the central subfield, and their ratio (RTA/ODRT), in the presence of diabetic macular edema or of inraretinal cystic fluid in neovascular age-related macular degeneration, to central retinal thickness and best-corrected visual acuity after anti-VEGF treatment with ME resolution. Methods: The optical coherence tomography images and medical records of 33 patients (41 eyes) with neovascular age-related macular degenera...
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
Purpose: To investigate longitudinal changes of outer nuclear layer (ONL) thickness in patients with retinal pigment epithelium tears secondary to neovascular age-related macular degeneration. Methods: This is an institutional retrospective interventional case series. Twenty-six eyes of 22 patients with retinal pigment epithelium tears identified between April 2009 and March 2015. The patients underwent intravitreal injection of anti-vascular endothelial growth factor agents as needed. Volume scans of optical coherence tomography at first diagnosis of tear (baseline) and after 12 months were analyzed. Outer nuclear la...
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
Conclusion: Drywall dissolves in the eye and becomes denser over time as air in the drywall is replaced by fluid. This study identified Hounsfield Units specific to intraocular drywall foreign body over time.
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
Failings that allowed the Gosport hospital scandal to happen are probably being repeated at other NHS services but not being identified because of the Department of Health and Social Care ’s “desire not to know”, a leading expert on hospital mortality has claimed.
Source: Nursing Times - Category: Nursing Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
More News: Boniva | Calcium | Disability | Funding | Health | Health Management | Hormones | Hyperparathyroidism | Internal Medicine | International Medicine & Public Health | National Institutes of Health (NIH) | Orthopaedics | Osteoporosis | PET Scan | Study | Universities & Medical Training | Vitamins | Women | X-Ray