Estimating the critical immunity threshold for preventing hepatitis A outbreaks in men who have sex with men

Research Articles D. G. REGAN, J. G. WOOD, C. BENEVENT, H. ALI, L. WATCHIRS SMITH, P. W. ROBERTSON, M. J. FERSON, C. K. FAIRLEY, B. DONOVAN, M. G. LAW, Epidemiology &Infection, Volume 144 Issue 07, pp 1528-1537Abstract
Source: Epidemiology and Infection - Category: Epidemiology Source Type: research

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Since January 2018, there have been 171 cases of hepatitis A reported in 36 counties in Pennsylvania. This year alone, there have been more than 60 cases confirmed of the liver disease.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
In just seven months, 86 people in South Carolina have been diagnosed with hepatitis A, which typically sickens just 19 a year, prompting the state to declare an outbreak amid a 300% surge in US cases.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Florida reported 92 hepatitis A cases last week, bringing the total to 1,129 cases this year as an outbreak continues to grow, according to numbers posted Monday on the state Department of Health website. The total is more than double the 548 cases reported in all of 2018. In the four previous years, the highest number of cases was 276 in 2017. Hepatitis A, which can cause liver damage, can be spread through such things as food or drinks that have been contaminated with fecal matter from people…
Source: bizjournals.com Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Source Type: news
Although 2016 saw two outbreaks of hepatitis A caused by contaminated food, the main reason for outbreaks has been the living conditions of drug addicts and the homeless.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Abstract Hepatitis A virus (HAV) is primarily transmitted fecal-orally after close contact with an infected person (1); it is the most common cause of viral hepatitis worldwide, typically causing acute and self-limited symptoms, although rarely liver failure and death can occur (1). Rates of hepatitis A had declined by approximately 95% during 1996-2011; however, during 2016-2018, CDC received approximately 15,000 reports of HAV infections from U.S. states and territories, indicating a recent increase in transmission (2,3). Since 2017, the vast majority of these reports were related to multiple outbreaks of infect...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
Florida has had a reported 1,037 cases of the liver disease hepatitis A this year, nearly double the amount reported for all of 2018, according to numbers posted on the state Department of Health website. The numbers, as of Saturday, show a continued escalation of the contagious disease. Health officials say the outbreak started last year, when the state had 548 cases. That was more than double the 276 cases in 2017 and far more than the 122 cases in 2016. The new Department of Health numbers…
Source: bizjournals.com Health Care News Headlines - Category: Health Management Source Type: news
Mark K. Slifka1* and Ian J. Amanna2 1Division of Neuroscience, Oregon National Primate Research Center, Oregon Health &Science University, Beaverton, OR, United States2Najít Technologies, Inc., Beaverton, OR, United States Vaccines play a vital role in protecting our communities against infectious disease. Unfortunately, some vaccines provide only partial protection or in some cases vaccine-mediated immunity may wane rapidly, resulting in either increased susceptibility to that disease or a requirement for more booster vaccinations in order to maintain immunity above a protective level. The durability of a...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Disease outbreaks resembling hepatitis A have been known since antiquity. However, it was not until World War II when two forms of viral hepatitis were clearly differentiated. After the discovery of Australia antigen and its association with hepatitis B, similar methodologies were used to find the hepatitis A virus. The virus was ultimately identified when investigators changed the focus of their search from serum to feces and applied appropriate technology.
Source: Cold Spring Harbor perspectives in medicine - Category: Research Authors: Tags: Enteric Hepatitis Viruses RETROSPECTIVE Source Type: research
by Lei Cao, Pi Liu, Pan Yang, Qiang Gao, Hong Li, Yao Sun, Ling Zhu, Jianping Lin, Dan Su, Zihe Rao, Xiangxi Wang Hepatitis A virus (HAV), an enigmatic and ancient pathogen, is a major causative agent of acute viral hepatitis worldwide. Although there are effective vaccines, antivirals against HAV infection are still required, especially during fulminant hepatitis outbreaks. A more in-depth understanding of t he antigenic characteristics of HAV and the mechanisms of neutralization could aid in the development of rationally designed antiviral drugs targeting HAV. In this paper, 4 new antibodies—F4, F6, F7, and F9&mda...
Source: PLoS Biology: Archived Table of Contents - Category: Biology Authors: Source Type: research
A worker at U.S. Chili in Camp Washington has been diagnosed with hepatitis A, and the Cincinnati Health Department is advising some people who ate at the restaurant earlier this month to get vaccinated.   This is the first instance that risk of exposure from a food handler has been identified in the city of Cincinnati since a 2018 outbreak of hepatitis A in Ohio.  The rare but highly contagious liver disease usually spreads when someone unknowingly ingests the virus from food, drinks or objects …
Source: bizjournals.com Health Care:Physician Practices headlines - Category: American Health Authors: Source Type: news
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