Even when women aren't obese, PCOS can mean pregnancy problems

(Reuters Health) - Women who suffer from a leading cause of infertility that can be made worse by obesity may not be able to escape pregnancy problems just by maintaining a normal weight, a recent study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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ConclusionCompared to non-PCOS patients, PCOS patients had greater postoperative ΔBMI and %EWL at 1 year. The majority of patients becoming pregnant after VSG were previously nulliparous. This study shows that VSG is effective for weight loss in PCOS patients with obesity and may positively augment effect fertility rates.
Source: Obesity Surgery - Category: Surgery Source Type: research
Authors: Artini PG, Obino MER, Sergiampietri C, Pinelli S, Papini F, Casarosa E, Cela V Abstract INTRODUCTION: Polycystic ovary syndrome (PCOS) is a common cause of female infertility affecting multiple aspects of a women's health. Areas covered: The aim of this review is to summarize the existing evidence on the treatment of PCOS patients and to examine the actual available therapies to overcome the problem of infertility and improve the outcome of pregnancy. We analyse different treatment strategies such as lifestyle modification, bariatric surgery, insulin sensitizing agents, inositol, clomiphene citrate (CC), a...
Source: Expert Review of Endocrinology and Metabolism - Category: Endocrinology Tags: Expert Rev Endocrinol Metab Source Type: research
Abstract Context: Women with PCOS are at increased risk for pregnancy complications possibly related to pre-existing obesity and potentially to excessive gestational weight gain (GWG). Objectives: To assess the contributions of pre-existing diagnosis and preconception weight on GWG and perinatal outcomes. Research Design and Methods: Prospective cohort study of singleton pregnancies in PCOS(N =164) and ovulatory controls(N = 176) conceiving from infertility treatment. Main Outcome measures: GWG, birthweight, pregnancy complications. Results: From pre-conception baseline, normal-weight PCOS women gai...
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
CONCLUSION: First line management of infertility once a diagnosis of PCOS is made should include weight loss and exercise with goals to below class 2 obesity (BMI
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
CONCLUSIONS: Preconception intervention with low-dose liraglutide added to metformin is superior to metformin alone in increasing PRs per ET and cumulative PRs in infertile obese women with PCOS, despite comparable weight reduction in both groups. A potential direct crosstalk between GLP-1 and reproductive system needs further exploration. PMID: 29703793 [PubMed - as supplied by publisher]
Source: European Journal of Endocrinology - Category: Endocrinology Authors: Tags: Eur J Endocrinol Source Type: research
(Natural News) According to the results of a study, women who take metformin, a common diabetes medication, could be putting their children at increased risk of being obese or overweight. More pregnant women with gestational diabetes or polycystic ovary syndrome (PCOS) are taking metformin to treat their conditions. PCOS usually causes infertility, and the condition can put...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Men and women follow the Wheat Belly lifestyle and can undergo important and sometime startling hormonal changes. Though results vary with stage of life—young adults, middle-aged, older—there are a variety of hormonal changes that women and men typically experience, some in concert, others independently. Such hormonal shifts can be powerful and part of the health-restoring menu of changes that develop with this lifestyle. They can even improve a relationship in a number of ways, both physically and emotionally, especially if we weave in some of the newer Wheat Belly/Undoctored concepts and practices such as oxy...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Wheat Belly Lifestyle estradiol estrogen hormonal hormones Inflammation low-carb oxytocin testosterone Thyroid Weight Loss Source Type: blogs
Abstract The increasing prevalence of morbid obesity in Germany is associated with an increasing number of metabolic surgical interventions. Short-term surgical and long-term metabolic complications - such as nutrient deficiencies - are the main risks of metabolic surgery and the resulting malabsorption. Obesity, especially morbid obesity, is associated with a high incidence of female infertility. One important cause of female infertility in obese women is the polycystic ovary syndrome, with 6 - 10%. Metabolic surgery significantly increases the fertility of obese women. The positive effect of obesity surgery ...
Source: Zentralblatt fur Chirurgie - Category: Surgery Authors: Tags: Zentralbl Chir Source Type: research
AbstractSTUDY QUESTIONWhat are the impacts of elevated testosterone (T) and an obesogenic western-style diet (WSD), either independently or together, on fertility and metabolic adaptations of pregnancy in primates?SUMMARY ANSWERTestosterone increases the time to achieve pregnancy, while a WSD reduces overall fertility, and the combination of testosterone and WSD additionally impairs glucose tolerance and causes pregnancy loss.WHAT IS KNOWN ALREADYBoth hyperandrogenemia and obesity are hallmarks of polycystic ovary syndrome, which is a leading cause of infertility among women worldwide. Female macaques receiving T and WSD b...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research
Conclusion Polycystic ovary syndrome is associated with hypertensive disorders in pregnancy. This association only occurs among underweight and obese women and not among normal-weight and slightly overweight women.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
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