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You're More Likely To Have A Heart Attack If You Have Endometriosis

(Reuters Health) – Women with an excess growth of uterine lining tissue may also be at higher risk of coronary heart disease, according to a new study. The condition, called endometriosis, affects up to five million women in the U.S. Uterine tissue can grow on the ovaries, behind the uterus or on the bowels or bladder and can cause pain, infertility and very heavy periods. “Many girls and women do not realize that distressing menstrual cramps and pelvic pain can be due to endometriosis,” said senior study author Stacey A. Missmer, director of Epidemiologic Research in Reproductive Medicine at Brigham and Women’s Hospital in Boston. “Girls and women can be treated through surgery that removes the endometriosis lesions or by hormonal medications including oral contraceptives,” but there is no outright cure, Missmer told Reuters Health by email. The researchers used data on more than 116,000 women in the Nurses’ Health Study II, which ran from 1989 to 2009 – including about 5,200 women with surgically confirmed endometriosis. Those with endometriosis were more likely than others to suffer a heart attack, to have coronary bypass or stent surgery, or to have angina, the chest pain that can be a sign of coronary artery disease. The increased risk for these conditions was highest for women up to age 40, who were about three times as likely to have any combination of the heart disease end points as those without endometriosis. The diffe...
Source: Science - The Huffington Post - Category: Science Source Type: news

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In conclusion, Buxus sempervirens leaf extract may be helpful in controlling the development of hyperlipidemia as well as atherosclerosis in diabetic animals. PMID: 29669507 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research
CONCLUSION: The increased or decreased activity of these two genes as a result of genetic changes and the development of thrombosis are a challenging and contradictory matter, and the study of genetic variability in ADAMTS13 and vWF genes may be helpful in the diagnosis of thrombotic disorders. PMID: 29669506 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research
In conclusion, these result suggested that the Chinese herbal formula HJF reduced hepatic steatosis maybe through decreasing certain gut bacteria (such as Enterobacteriaceae bacteria and F. rappini), alleviating intestinal endotoxemia and reducing NLRP3 inflammasome activation. PMID: 29675053 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Authors: Alemu A, Tamiru W, Nedi T, Shibeshi W Abstract Background: Pain and inflammation are the major health problems commonly treated with traditional remedies mainly using medicinal plants. Leonotis ocymifolia is one of such medicinal plants used in folkloric medicine of Ethiopia. However, the plant has not been scientifically evaluated. The aim of this study was to evaluate analgesic and anti-inflammatory effects of the 80% methanol leaves extract of Leonotis ocymifolia using rodent models. Method: The central and peripheral analgesic effect of the extract at 100, 200, and 400 mg/kg dose levels was ...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Authors: Cai Y, Wang Y, Zhi F, Xing QC, Chen YZ Abstract Treating type 2 diabetes mellitus (T2DM) using thiazolidinediones and biguanides can present several challenges for patients. Sanggua Drink (SGD) is a commonly used agent in traditional Chinese medicine, and it consists of Folium Mori, Fructus Momordicae Charantiae, Radix Puerariae Lobatae, and Rhizoma Dioscorea. The hypoglycemic effects and mechanisms of SGD extracts on insulin resistance in diabetic rats were investigated. SGD (1.24 g/kg orally) was verified in T2DM rats induced by a high-fat diet and streptozotocin. The results showed that SGD treat...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Authors: Sun K, Song X, Jia R, Yin Z, Zou Y, Li L, Yin L, He C, Liang X, Yue G, Cui Q, Yang Y Abstract Aim: Pain and inflammation are associated with many diseases in humans and animals. Galla Chinensis, a traditional Chinese medicine, has a variety of pharmacological properties. The purpose of this study was to evaluate analgesic and anti-inflammatory activities of Galla Chinensis through different animal models. Method: The analgesic activities were evaluated by hot-plate and writhing tests. The anti-inflammatory effects were assessed by ear edema, capillary permeability, and paw edema tests. The contents of ...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Authors: Fung C, Dinh P, Ardeshir-Rouhani-Fard S, Schaffer K, Fossa SD, Travis LB Abstract Testicular cancer has become the paradigm of adult-onset cancer survivorship, due to the young age at diagnosis and 10-year relative survival of 95%. This clinical review presents the current status of various treatment-related complications experienced by long-term testicular cancer survivors (TCS) free of disease for 5 or more years after primary treatment. Cardiovascular disease and second malignant neoplasms represent the most common potentially life-threatening late effects. Other long-term adverse outcomes include neuro...
Source: Advances in Urology - Category: Urology & Nephrology Tags: Adv Urol Source Type: research
69 y.o. female with severe kyphosis, scoliosis H/O recent compression Fx presents with right flank/abdominal pain. Big w/u by PCP and GI negative. On physical exam I note that PSIS is only a few finger breaths below her rib. Thinking that pain is mechanical in origin due to friction I bring her in and block two intercostal nerves with 100% pain relief for duration of bupivacaine. What would you next move be? Repeat block with steroid, consider surgical resection of rib? She has been on COT... Strange flank pain case
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Source Type: forums
“Sometimes I think I need a spare heart to feel all the things I feel.” — Sanober Khan I felt her agony and loneliness as if it were my own. Even as I write that sentence, my eyes well up and heaviness fills my heart. Then, I’m reminded to apply the advice I give others. My mom was a special person, a sensitive soul just like me. Actually, I’m so much like she was, yet so different. One of the differences between us is that I had an opportunity to observe her life’s challenges. I saw her challenges reflected within myself and made a conscious choice to find healthy ways to cope. You see,...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Parenting Personal Publishers Self-Help Tiny Buddha Boundaries compassionate Emotions Empathy Feelings Highly Sensitive Person sensitive people Sensitivity Sympathy Source Type: blogs
In this study, we evaluated the effects of a novel liver-specific LXR inverse agonist, SR9243, on antifibrosis in NASH mice. A high-cholesterol diet was employed to induce NASH in BALB/c mice by either carbon tetrachloride (CCL4) administration or bile-duct ligation (BDL). Once NASH was induced, mice were treated with SR9243 for one month by intraperitoneal (i.p.) injection. Liver tissues were collected to determine the degree of fibrosis and intrahepatic inflammation via pathological examination and QPCR; serum was collected to analyze the plasma lipid levels and liver function by clinical biochemistry. The mice developed...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
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