You're More Likely To Have A Heart Attack If You Have Endometriosis

(Reuters Health) – Women with an excess growth of uterine lining tissue may also be at higher risk of coronary heart disease, according to a new study. The condition, called endometriosis, affects up to five million women in the U.S. Uterine tissue can grow on the ovaries, behind the uterus or on the bowels or bladder and can cause pain, infertility and very heavy periods. “Many girls and women do not realize that distressing menstrual cramps and pelvic pain can be due to endometriosis,” said senior study author Stacey A. Missmer, director of Epidemiologic Research in Reproductive Medicine at Brigham and Women’s Hospital in Boston. “Girls and women can be treated through surgery that removes the endometriosis lesions or by hormonal medications including oral contraceptives,” but there is no outright cure, Missmer told Reuters Health by email. The researchers used data on more than 116,000 women in the Nurses’ Health Study II, which ran from 1989 to 2009 – including about 5,200 women with surgically confirmed endometriosis. Those with endometriosis were more likely than others to suffer a heart attack, to have coronary bypass or stent surgery, or to have angina, the chest pain that can be a sign of coronary artery disease. The increased risk for these conditions was highest for women up to age 40, who were about three times as likely to have any combination of the heart disease end points as those without endometriosis. The diffe...
Source: Science - The Huffington Post - Category: Science Source Type: news

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Cognitive behavioral therapy, offered in-office or online, may reduce pain and opioid use in addition to improving sleep and mood, new research suggests.Medscape Medical News
Source: Medscape Internal Medicine Headlines - Category: Internal Medicine Tags: Psychiatry News Source Type: news
ConclusionsThe primary ingredients in cannabis, tetrahydrocannabinol (THC) and cannabidiol (CBD), have been made available in numerous forms and formulations to treat multiple medical conditions, and recreational access to marijuana is increasing. Of particular importance to the surgeon may be their effects on prolonging intestinal motility, decreasing inflammation, increasing hunger, mitigating pain, and reducing nausea and vomiting. Perioperative use of medicinal or recreational marijuana will become increasingly prevalent, and the surgeon should be aware of the positive and negative effects of these cannabinoids.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
This study assessed the efficacy and safety of tofacitinib in Chinese patients with RA enrolled in Phase 3 and long-term extension (LTE) studies. Methods: ORAL Sync was a 1-year, randomized, placebo-controlled, Phase 3 trial. Patients received tofacitinib 5 or 10 mg twice daily (BID) or placebo advanced to tofacitinib 5 or 10 mg BID at 3 or 6 months. All patients remained on ≥1 background conventional synthetic disease-modifying antirheumatic drug. ORAL Sequel is an open-label LTE study (data-cut: March 2015; data collection and analyses were ongoing, and study database was not locked at the time of analysis; study...
Source: Chinese Medical Journal - Category: General Medicine Authors: Tags: Chin Med J (Engl) Source Type: research
Two Albuquerque pain management clinics specializing in musculoskeletal pain have merged to create one of the largest pain management groups in New Mexico. The two pain management providers, Quadra Health Institute and USA Pain Clinics, merged Nov. 1, according to a press release. USA Pain Clinics has two locations, one in Albuquerque and one in Rio Rancho. Quadra Health Institute has one location in Albuquerque. Each will continue to work under it s individual brand, but with a merged group of…
Source: bizjournals.com Health Care News Headlines - Category: Health Management Authors: Source Type: news
Publication date: Available online 14 November 2018Source: Journal of Clinical Orthopaedics and TraumaAuthor(s): Raju Vaishya, Ankur Kansagra, Vipul Vijay, Abhishek Vaish, Amit Kumar AgarwalAbstractOsteochondritis dissecans (OCD) of the knee joint affects subchondral bone first, and then it involves the articular cartilage. It can cause pain, effusion and loose body formation. Nonoperative treatment is for the stable lesion, but if the lesion is unstable and symptomatic, then operative management is needed. Short term goal of the treatment is pain relief, and the long-term goal is the prevention of early arthritis. Surgica...
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research
Publication date: December 2018Source: Joint Bone Spine, Volume 85, Issue 6Author(s): Bilade Cherqaoui, Linda Rossi-Semerano, Sophie Georgin-Lavialle, Perrine Dusser, Caroline Galeotti, Maryam Piram, Véronique Hentgen, Isabelle Touitou, Isabelle Koné-PautAbstractObjectivesChildren with Familial Mediterranean fever may suffer from musculoskeletal involvement, somewhat difficult to distinguish from juvenile spondyloarthritis. The association of these two diseases has been scarcely reported in children. Objective of this work was to define the association of familial Mediterranean fever and juvenile spondyloarth...
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
Publication date: December 2018Source: Joint Bone Spine, Volume 85, Issue 6Author(s): Christelle Darrieutort-Laffite, Frédéric Blanchard, Benoit Le GoffAbstractCalcific tendonitis of the rotator cuff is due to apatite deposits in the shoulder tendons. Patients affected by calcific tendonitis have chronic shoulder pain and disability. Although the disease is frequent, about 10 to 42% of painful shoulders, mechanisms leading to this pathological mineralization are still largely unknown. Research reported in the 1990s suggested that the formation of calcific deposits is linked to cells looking like chondrocytes ...
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
Source: BMJ News - Category: General Medicine Source Type: research
ConclusionsWC and PA were considered the parameters most related to MetS by principals components analysis. The diagnosis of MetS presented an inverse relation with the spirometrics parameters. Elevation of BP and WC were the predictors of the CFV% reduction.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Conclusions: Our results indicate that HOTAIRM1-1 is downregulated in OA cartilages, and its downregulation may inhibit MSCs viability, induce apoptosis and suppress differentiation via regulating miR-125b/BMPR2 axis. JNK/MAPK/ERK pathway may be a possible downstream mechanism to mediate the role of HOTAIRM1-1 in OA development.Graphical abstract
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
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