The 'Pinhole' Cancer Treatment You've Probably Never Heard of

Imagine an exquisitely precise cancer therapy procedure done through a small opening in the body that can: Kill tumor cells, shrink tumors, or regrow the healthy part of a cancerous organ. Deliver chemotherapy or radiation directly to the cancer site. Usually be done as an outpatient procedure with fewer side effects than conventional treatments like chemotherapy. Potentially treat many types of cancer, either alone or combined with other therapies. Sounds too good to be true, right? Not necessarily, since this type of therapy, called interventional oncology, is now being performed hundreds of times every day by specialists in a medical field that is unfamiliar to many cancer patients. Many predict this fast-growing specialty will soon join medical, surgical and radiation oncology as the fourth pillar of cancer care. Pioneers in Precision Medicine Interventional oncology is an image-guided, minimally invasive surgery done by radiologists that uses imaging scans as maps to identify the location of tumors and blood vessels as pathways to kill tumors or shrink and prepare them for removal. Most procedures are either outpatient or require a brief overnight stay in the hospital. Recovery time is minimal; some patients are active as early as the next day. Plus, there are rarely the physical complications associated with surgery nor the side effects with chemotherapy or external radiation, like hair loss. Interventional oncology is a subset of the field of interventional radiolog...
Source: Science - The Huffington Post - Category: Science Source Type: news

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Abstract On December 20, 2017, the Food and Drug Administration granted regular approval to pertuzumab in combination with trastuzumab and chemotherapy for the adjuvant treatment of patients with HER2-positive early breast cancer (EBC) at high risk of recurrence. Approval was based on data from the APHINITY trial, which randomized patients to receive pertuzumab or placebo in combination with trastuzumab and chemotherapy. After 45.4 months median follow-up, the proportion of invasive disease-free survival (IDFS) events in the intent-to-treat population was 7.1% (n=171) in the pertuzumab arm and 8.7% (n=210) for pla...
Source: Clinical Cancer Research - Category: Cancer & Oncology Authors: Tags: Clin Cancer Res Source Type: research
CONCLUSION: Chemotherapy-related ADRs among cancer patients are worrisome. It has a negative impact on patient quality of life and in addition increases cost of therapy. It is found that timely reporting of chemotherapy-related ADRs and having an effective ADR monitoring system in place ensure preventability of the ADRs in many cases. Oncologists, Radiotherapists and Onco-surgeons should be actively involved in ADR reporting (Onco-Pharmacovigilance) and exchange constructive information, update and educate each other about appropriate use of anticancer drugs. Onco-pharmacovigilance is the need of the hour and could be of i...
Source: Indian Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Source Type: research
This study evaluated the physicochemical and mineralogical properties, mobile chemical species bioavailability and translocation in Brassica juncea and Spinacea oleracea L. plants of a South African coal-fired power utility. Coal-fly-ash (CFA) disposal is associated with various environmental and health risks, including air, soil, surface, and groundwater pollution due to the leaching of toxic heavy metals; these ends up in food webs affecting human health, while repeated inhalation causes bronchitis, silicosis, hair loss, and lung cancer. The morphology and chemical and mineralogical composition of CFA were determined usi...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
You're reading 4 Key Ingredients to Avoid in Cosmetics, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. As you walk down a store’s beauty aisle, it’s easy to choose the most popular brands and products that line the shelves. After all, they are on sale and the labels claim to be organic or all natural. Despite these perks, what consumers fail to realize is that these labels can deceive consumers into believing their items are safe and toxin-free. The truth is the beauty market across the United States has lack...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: featured health and fitness self improvement beauty pickthebrain toxic Source Type: blogs
Abstract The molecular chaperones Hsp70 and Hsp90 bind and fold a significant proportion of the proteome. They are responsible for the activity and stability of many disease-related proteins including those in cancer. Substantial effort has been devoted to developing a range of chaperone inhibitors for clinical use. Recent studies have identified the oncogenic ribonucleotide reductase (RNR) complex as an interactor of chaperones. While several generations of RNR inhibitor have been developed for use in cancer patients, many of these produce severe side effects such as nausea, vomiting and hair loss. Development of...
Source: Current Genetics - Category: Genetics & Stem Cells Authors: Tags: Curr Genet Source Type: research
Conclusion: The rash on the scalp described in this report enriches our knowledge on the clinical characteristics of MSF.
Source: Medical Principles and Practice - Category: Internal Medicine Source Type: research
CONCLUSIONS: Findings suggest that negative cultural meanings of hair and hair loss are pervasive and may drive social avoidance and camouflage behaviours in people with AA. Normalising social interactions with healthcare practitioners, significant others and peers were cited as pivotal to positive adjustment. Support groups and online forums were highly valued particularly as few had been offered specialist psychological support. Future research should develop and evaluate psychological support to address the specific challenges of living with AA. This article is protected by copyright. All rights reserved. PMID: 305...
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
In this report, we present four patients with a distinct neurometabolic disorder associated with de novo heterozygous, gain‐of‐function variants in theODC1 gene. This disorder presents with global developmental delay, ectodermal abnormalities including alopecia, absolute or relative macrocephaly, and characteristic facial dysmorphisms. Neuroimaging variably demonstrates white matter abnormalities, prominent Virchow –Robin spaces, periventricular cysts, and abnormalities of the corpus callosum. Plasma clinical metabolomics analysis demonstrates elevation ofN‐acetylputrescine, the acetylated form of putrescine, w...
Source: American Journal of Medical Genetics Part A - Category: Genetics & Stem Cells Authors: Tags: RESEARCH ARTICLE Source Type: research
Conclusions: The CBT therapies Ipi and Nivo, in combination with BV, are overall both well tolerated over time, although BV/Ipi has a higher overall AE burden. Neither regimen has significant cumulative immune toxicity. Results of this analysis should be interpreted in the context of limited number of pts in both cohorts. A larger scale examination of this analysis is planned to incorporate both phase 1 and the ongoing phase 2 components of E4412. Compared with conventional tox analysis, ToxT delineated important additional and clinically relevant depictions of AEs over time and adds a more comprehensive assessment of the ...
Source: Blood - Category: Hematology Authors: Tags: 904. Outcomes Research-Malignant Conditions: Outcomes in Lymphoid Malignancies and Stem Cell Transplant Source Type: research
Conclusion: YY-20394 is well tolerated and with promised objective response rates in patients with relapsed or refractory B-cell malignancies. The current first-in-human study for dose escalation and dose expansion is still ongoing.DisclosuresSong: Peking University Cancer Hospital (Beijing Cancer Hospital): Employment. Zhu: Beijing Cancer Hospital: Employment.
Source: Blood - Category: Hematology Authors: Tags: 623. Mantle Cell, Follicular, and Other Indolent B-Cell Lymphoma-Clinical Studies Source Type: research
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