IMPACT: a whole-exome sequencing analysis pipeline for integrating molecular profiles with actionable therapeutics in clinical samples

Conclusion IMPACT provides a new bioinformatics strategy to delineate candidate somatic variants and actionable therapies. This approach can be applied to other patient tumor samples to discover effective drug targets for personalized medicine.IMPACT is publicly available at http://tanlab.ucdenver.edu/IMPACT.

Source: Journal of the American Medical Informatics Association - March 27, 2016 Category: Information Technology Authors: Hintzsche, J., Kim, J., Yadav, V., Amato, C., Robinson, S. E., Seelenfreund, E., Shellman, Y., Wisell, J., Applegate, A., McCarter, M., Box, N., Tentler, J., De, S., Robinson, W. A., Tan, A. C. Tags: Research and Applications Source Type: research