Differential Melatonin Alterations in Cerebrospinal Fluid and Serum of Patients with Major Depressive Disorder and Bipolar Disorder

Melatonin, which plays an important role for regulation of circadian rhythms and the sleep/wake cycle has been linked to the pathophysiology of major depressive and bipolar disorder. Here we investigated melatonin levels in cerebrospinal fluid (CSF) and serum of depression and bipolar patients to elucidate potential differences and commonalities in melatonin alterations across the two disorders.
Source: Comprehensive Psychiatry - Category: Psychiatry Authors: Source Type: research