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Your Dentist Is More Important to Your General Health Than You May Realize

Most people view their twice-yearly visits to the dentist as little more than a cleaning and a check-up. But in reality, those visits are much more important than you probably realize. That's because your dentist is looking inside your mouth for a lot more than cavities. Plenty of medical conditions -- including some alarming ones! -- manifest in the mouth, which is the part of your body your dentist knows the most about. In fact, it's possible that your dentist is able to alert you of a potentially serious condition long before you even think about going to a primary care doctor. Here's a list of some of the medical conditions that your dentist may detect. Acromegaly When a pituitary adenoma (cancer) occurs, it causes the gland to secrete excess growth hormone. While this hormone is essential for early development, allowing it to go unchecked results in multiple systemic complications, which can eventually lead to death. What your dentist may notice are sudden and increased spacing between your teeth, and the formation of an anterior open bite. Osteogenesis Imperfecta (OI) The most common inherited bone disease, OI results in a deficiency to produce collagen, resulting in brittle bones prone to fracture. Atticus Shaffer (Brick from ABC's The Middle) has the condition. People are usually diagnosed with OI if they break bones in situations where a person normally would not. However, there are key signs in your mouth a dentist can look for that may provide an early diagnosis....
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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We describe the experimental and computational approaches undertaken both in humans and model organisms to identify these interactions. Finally we discuss some of the identified targets with licensed drugs, inhibitors in clinical trials or with compounds under development. PMID: 28941356 [PubMed - in process]
Source: Journal of integrative bioinformatics - Category: Bioinformatics Tags: J Integr Bioinform Source Type: research
Sen. John McCain opened up Sunday about the moment he was diagnosed with an aggressive, often deadly form of brain cancer earlier this year. In a forthcoming interview on CBS’ 60 Minutes, the Arizona senator spoke about what it was like when doctors told him he had glioblastoma, an aggressive form of brain cancer. At the time, McCain was visiting his doctor at the Mayo Clinic in Phoenix to check out a blood clot in his eye. “As you know, doctors are interesting,” he told CBS, adding that he repeatedly told his doctors to “tell it to me straight.” It was only days after the operation that doct...
Source: TIME.com: Top Science and Health Stories - Category: Consumer Health News Authors: Tags: Uncategorized John McCain onetime Source Type: news
BRITAIN ’S obesity epidemic has put hundreds of thousands at risk of heart disease and stroke, analysis shows.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Authors: Harris LA, Baffy N Abstract Irritable bowel syndrome (IBS), which is characterized by recurrent abdominal pain and disordered bowel habits, is one of the most common functional bowel disorders. IBS is a substantial burden on both patient health-related quality of life and health care costs. Several pathophysiologic mechanisms have been postulated for the occurrence of IBS, including altered gastrointestinal motility, visceral hypersensitivity, changes in gut permeability, immune activation, gut-brain dysregulation, autonomic nervous system dysfunction, and changes in the gut microbiota. Of note, both quali...
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
CONCLUSION: The post-treatment pathological evaluation by biopsies (targeted with MRI or, perhaps in a near future, with innovative ultrasonography) is the corner stone of oncological evaluation of ablative therapies. Ongoing trials will allow to standardize the follow-up and determine the best indication and the best techniques in order to optimize oncological and functional results for each patient treated. PMID: 28939336 [PubMed - as supplied by publisher]
Source: Progres en Urologie - Category: Urology & Nephrology Tags: Prog Urol Source Type: research
Authors: Christensen MK, Niclasen BV, Iburg KM Abstract With a low breast cancer incidence and low population density, Greenland is geographically and organisationally challenged in implementing a cost effective breast cancer screening programme where a large proportion of the Greenlandic women will have to travel far to attend. The aim of this paper is to evaluate the cost effectiveness and cost utility of different strategies for implementing population-based breast cancer screening in Greenland. Two strategies were evaluated: Centralised screening in the capital Nuuk and decentralised screening in the five munic...
Source: International Journal of Circumpolar Health - Category: International Medicine & Public Health Tags: Int J Circumpolar Health Source Type: research
Almost a year after Colin Kaepernick first knelt as the U.S. national anthem played ahead of a game, his silent protest has once again become the subject of national attention — this time, because President Trump has launched a days-long tirade at players who have joined the movement. But while a year ago, it was the act of kneeling in protest police treatment of African Americans that captured the most attention, in 2017, it appears to be Trump’s unconventional response to the act. Since Friday, the Commander in Chief has called for NFL fans to walk out of games if they saw a player kneel, and added on Twitter...
Source: TIME.com: Top Science and Health Stories - Category: Consumer Health News Authors: Tags: Uncategorized Barack Obama Donald Trump onetime Source Type: news
Authors: Barani B, Rajasingh S, Rajasingh J Abstract Cardiovascular diseases are the number one cause of death globally with an estimated 7.4 million people dying from coronary heart disease. Studies have been conducted to identify the therapeutic utility of exosomes in many diseases, including cardiovascular diseases. It has been demonstrated that exosomes are immune modulators, can be used to treat cardiac ischemic injury, pulmonary hypertension and many other diseases, including cancers. Exosomes can be used as a biomarker for disease and cell-free drug delivery system for targeting the cells. Many studies sugge...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Ding S, Fan Z, Lin C, Dai Q, Zhou J, Huang H, Xu Y, Zhong C Abstract Despite years of researches, cardiovascular disease (CVD) remains the most common cause of death around the world. Lots of studies showed that by pretreating with short nonfatal ischemia in in situ organ or distant organ, one could develop tolerance to the following fatal ischemia. The process is called ischemic preconditioning (IPC). IPC prepare the heart for damage by producing inflammatory signals, miRNA, neuro system stimulation and exosomes. Among them, exosomes have been gaining increasing interest since it is characterized by its c...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Bei Y, Chen T, Banciu DD, Cretoiu D, Xiao J Abstract Circulating exosomes could arrive in distant tissues via blood circulation, thus directly communicating with target cells and rapidly regulating intracellular signalings. Circulating exosomes and exosomal cargos are critically involved in cardiovascular pathophysiology, such as cardiomyocyte hypertrophy, apoptosis, and angiogenesis. Circulating exosomes enriched with various types of biological molecules can be changed not only in the number but also in the composite cargos upon cardiac injury, such as myocardial infarction, myocardial ischemia reperfusi...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
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