Tumour infiltrating lymphocytes correlate with improved survival in patients with oesophageal adenocarcinoma

Discussion Our results establish an association of TILs and survival in OAC, as seen in other solid tumours, and identify particular TIL subsets that are present at higher levels in patients who responded to NAC compared to non-responders. These findings highlight potential therapeutic strategies in EAC based on utilising the host immunological response and highlight the immune responses biomarker potential.

http://link.springer.com/10.1007/s00262-016-1826-5

Source: Cancer Immunology, Immunotherapy - March 27, 2016 Category: Cancer & Oncology Source Type: research