Paracetamol, Ibuprofen, and Recurrent Major Cardiovascular and Major Bleeding Events in 19 120 Patients With Recent Ischemic Stroke [Clinical Sciences]

Conclusions— There was a weak and inconsistent signal for association between paracetamol or ibuprofen and MACE or major bleeding, which may be related to either a genuine but modest effect of these drugs or to residual confounding. Clinical Trial Registration— http://www.isrctn.com. Unique identifier: ISRCTN66157730.

http://stroke.ahajournals.org/cgi/content/short/47/4/1045?rss=1

Source: Stroke - March 27, 2016 Category: Neurology Authors: Gonzalez-Valcarcel, J., Sissani, L., Labreuche, J., Bousser, M.-G., Chamorro, A., Fisher, M., Ford, I., Fox, K. M., Hennerici, M. G., Mattle, H. P., Rothwell, P. M., Steg, P. G., Vicaut, E., Amarenco, P., for the PERFORM Investigators Tags: Intracranial Hemorrhage, Ischemic Stroke, Transient Ischemic Attack (TIA) Clinical Sciences Source Type: research