New norlignans and flavonoids of Dysosma versipellis

Publication date: June 2016 Source:Phytochemistry Letters, Volume 16 Author(s): Yue Zheng, Yang-Guo Xie, Yu Zhang, Tao Li, Hui-Liang Li, Shi-Kai Yan, Hui-Zi Jin, Wei-Dong Zhang Two new norlignans, dysosmanorlignans A and B (1–2); six new flavonoids, dysosmaflavones A–F (3–8); and 30 known compounds (9–38) were isolated from the roots of Dysosma versipellis. Their structures were determined by detailed analysis of MS and NMR spectroscopic data. Dysosmaflavones E and F both exhibited mild antibacterial activities against Streptococcus agalactiae, Pseudomonas aeruginosa, and Bacillus subtilis with MIC values ranging from 93.0 to 93.8μg/mL. Graphical abstract

Source: Phytochemistry Letters - March 25, 2016 Category: Chemistry Source Type: research