This Disease Can Still Get You Quarantined For Months -- And It's On The Rise

In August 2014, Kate O’Brien, a 34-year-old media producer from Brooklyn, found out she was expecting her second child. She was ecstatic. But this pregnancy didn't proceed like the first. For the next few months, O'Brien had a cold she couldn't shake. She woke up in the middle of the night drenched in sweat. She wanted to blame it on her pregnancy, yet she kept losing weight. She could barely eat. She coughed up balls of bloody mucus. Her throat burned. None of her doctors could figure out what was wrong. A physician sent her to Mount Sinai West Hospital in Manhattan in January 2015, when, at five months pregnant, she still couldn't gain any weight. "No one likes a skinny pregnant lady," she said. O'Brien expected to stay at the hospital overnight. She didn’t get a chance to say goodbye to her 2-year-old, Donny, but she figured she'd be home soon. She didn't walk out of the hospital for 75 days. @media (max-width: 499px) { .desktop { display: none; } } @media (min-width: 500px) { .mobile { display: none; } } The doctors at Mount Sinai diagnosed O'Brien with infectious tuberculosis. After a few days in the intensive care unit, she was shifted to a negative-pressure isolation room, which helps contain the infected air. Signs announcing "WARNING: Infectious Disease" were affixed to the room's airtight set of double doors. And all O'Brien could think about was what this meant for her unborn baby. The federal policy that governs medical isol...
Source: Science - The Huffington Post - Category: Science Source Type: news

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Publication date: March 2019Source: International Journal of Paleopathology, Volume 24Author(s): Kenji Okazaki, Hirofumi Takamuku, Shiori Yonemoto, Yu Itahashi, Takashi Gakuhari, Minoru Yoneda, Jie ChenAbstractThe earliest evidence of human tuberculosis can be traced to at least the early dynastic periods, when full-scaled wet-rice agriculture began or entered its early developmental stages, in circum-China countries (Japan, Korea, and Thailand). Early studies indicated that the initial spread of tuberculosis coincided with the development of wet-rice agriculture. It has been proposed that the adaptation to agriculture cha...
Source: International Journal of Paleopathology - Category: Pathology Source Type: research
Conclusions: In our study of patients with isolated elevations in amylase and/or lipase without acute pancreatitis who underwent EUS, approximately 50% had a pancreatobiliary finding, most commonly chronic pancreatitis or biliary sludge. PMID: 30646674 [PubMed - as supplied by publisher]
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research
Conclusions: For patients with suppressed HBV DNA, the efficacy of TDF monotherapy as maintenance therapy is comparable to that of entecavir plus TDF combination therapy. PMID: 30647735 [PubMed]
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
Researchers recently found that counties that had higher rates of opioid prescribing had nearly two times more babies born with their intestines outside of their bodies, a condition known as gastroschisis, compared with counties with low opioid prescribing rates.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
Other threats on WHO's radar include Ebola and other high-threat pathogens, antimicrobial resistance, vaccine'hesitancy,'weak primary healthcare, and noncommunicable diseases.Medscape Medical News
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news
ConclusionThe available evidence remains inconclusive but suggests that curcumin is a promising effective treatment option for the management of patients with OSF. Further well-designed clinical trials with large sample sizes and adequate follow-up periods are highly warranted.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
ConclusionLimited evidence exists on the effects of PRGF in different intraoral bone grafting procedures, with some benefit reported on soft tissue healing and post-operative symptomatology. As this platelet concentrate is commonly used in clinical practice, further research is needed to fully assess its clinical indications and effectiveness.
Source: Journal of Cranio Maxillofacial Surgery - Category: ENT & OMF Source Type: research
A 73-year-old female presenting with haemoptysis and dyspnoea was found to have a locally advanced left thyroid mass and vocal cord palsy. A CT scan of the neck and thorax and endoscopy demonstrated invasion into the tracheal lumen. Histopathology of the intraluminal tracheal mass confirmed a papillary thyroid cancer (PTC). The tumour was deemed unresectable due to local extent and patient comorbidities. TKI therapy with lenvatinib was used for 14 months. On serial scanning, a marked reduction in tumour volume from 31 × 59 × 32 mm to 17 × 28 × 22 mm was noted. This subsequently allowed a successful ...
Source: European Thyroid Journal - Category: Endocrinology Source Type: research
Publication date: Available online 16 January 2019Source: Molecular and Cellular EndocrinologyAuthor(s): Irida Kastrati, Svetlana Semina, Benjamin Gordon, Emily SmartAbstractEstrogen receptor (ER) is the most important factor in the pathophysiology of breast cancer. Consequently, modulation of ER activity has been exploited to develop drugs against ER + breast cancer, such as tamoxifen, referred to as endocrine therapies. With deeper understanding of ER mechanism of action, posttranslational modifications (PTMs) are increasingly recognized as important in mediating ER activity. Some ER PTMs such as phosphorylatio...
Source: Molecular and Cellular Endocrinology - Category: Endocrinology Source Type: research
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