Sex differences in the incidence of skin and skin‐related diseases in Olmsted County, Minnesota, United States, and a comparison with other rates published worldwide

Abstract Many skin and skin‐related diseases affect the sexes unequally, with attendant implications for public health and resource allocation. To evaluate better the incidence of skin and skin‐related diseases affecting males vs. females, we reviewed published population‐based epidemiology studies of skin disorders performed utilizing Rochester Epidemiology Project data. Females had a higher incidence of the following diseases: connective tissue diseases (scleroderma, morphea, dermatomyositis, primary Sjögren syndrome, systemic lupus erythematosus [not in all studies]), pityriasis rosea, herpes progenitalis, condyloma acuminatum, hidradenitis suppurativa, herpes zoster (except in children), erythromelalgia, venous stasis syndrome, and venous ulcers. Males had a higher incidence of psoriasis and psoriatic arthritis, basal cell carcinoma (exception, females aged ≤40 years), squamous cell carcinoma, and lentigo maligna. Incidence rates were equal in males and females for cutaneous malignant melanoma (exception, higher in females aged 18–39 years), lower‐extremity cellulitis, cutaneous nontuberculous mycobacterial infection, Behçet disease, delusional infestation, alopecia areata, and bullous pemphigoid. Many of the population‐based sex‐specific incidence rates of skin and skin‐related diseases derived from the Rochester Epidemiology Project are strikingly different from those estimated elsewhere. In general, females are more commonly affected ...
Source: International Journal of Dermatology - Category: Dermatology Authors: Tags: Review Source Type: research

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ConclusionMSUS is powerful in the detection of early RA regarding synovitis, joint effusion, tenosynovitis, and bone erosions, which were correlated with clinical and laboratory parameters.
Source: Academic Radiology - Category: Radiology Source Type: research
Publication date: Available online 22 January 2020Source: The Journal of Molecular DiagnosticsAuthor(s): Yi-Wei Tang, Lorena Lozano, Xin Chen, Troy D. Querec, Nora Katabi, Antonio Moreno-Docón, Hongmei Wang, Daniel Fix, Louise De Brot, Tracy A. McMillen, Ju-Yoon Yoon, Amparo Torroba, Youxiang Wang, Elizabeth R. Unger, Kay J. ParkAbstractRapid and accurate identification of human papillomavirus (HPV) is important for both clinical management and population screening. We performed analytic validation of Atila AmpFire Multiplex HPV assays on formalin-fixed, paraffin-embedded (FFPE) cervix/vulva and oropharynx diagnosti...
Source: The Journal of Molecular Diagnostics - Category: Pathology Source Type: research
Publication date: Available online 22 January 2020Source: The Journal of Molecular DiagnosticsAuthor(s): Aaron B. Beasley, Jacqueline Bentel, Richard J.N. Allcock, Tersia Vermeulen, Leslie Calapre, Timothy Isaacs, Melanie R. Ziman, Fred K. Chen, Elin S. GrayAbstractAnalysis of specific somatic copy number alterations (SCNAs) using multiplex ligation-dependent probe amplification (MLPA) is routinely used as prognostic test for uveal melanoma (UM). This technique requires relatively large amounts of input DNA, unattainable from many small fine needle aspirate biopsies. Herein we compared the use of MLPA with whole genome amp...
Source: The Journal of Molecular Diagnostics - Category: Pathology Source Type: research
CONCLUSION: The T-shaped linear-stapled cervical esophagogastric anastomosis is efficient, reliable, easy to perform, and associated with lower postoperative complication rate. PMID: 31955641 [PubMed - as supplied by publisher]
Source: Tumori - Category: Cancer & Oncology Tags: Tumori Source Type: research
CONCLUSION: As a result of the study the relationship of the alleles/genotypes of the IL1B rs16944, IL10 rs1800872, CTLA4 rs3087243, NFKB1 rs28362491 polymorphic loci and the TNFA rs1800629*A - LTA rs909253*G haplotype with the methotrexate efficacy in JIA was established (taking into account the differences by sex). PMID: 31958219 [PubMed - as supplied by publisher]
Source: Turkish Journal of Medical Sciences - Category: General Medicine Tags: Turk J Med Sci Source Type: research
This article provides an overview of liquid biopsy, its uses in cancer management, and its implications for nursing practice. PMID: 31961840 [PubMed - in process]
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Tags: Clin J Oncol Nurs Source Type: research
BY JESSICA DAMASSA, WTF HEALTH Almirall is a dermatology-focused pharmaceutical company based in Spain, and its investment in R&D for developing new therapeutics leads the way as the largest within the country’s pharma industry. It’s no surprise, then, that Almirall has also adopted a digital therapeutics and digital health strategy to augment it’s molecular innovations with a ‘beyond the pill’ approach. We sat down with Almirall’s first-ever Chief Digital Officer, Francesca Wuttke, to hear about the pharma company’s digital strategy which is centered on laying the framework for...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Health Tech Jessica DaMassa WTF Health Almirall Barcelona Health Hub Barcelona Health Hub Summit 2019 digital health Digital health funding digital therapeutics dtx Francesca Wuttke Pharma pharmaceuticals Source Type: blogs
In conclusion, the molecular mechanism of anti-HCC of B. batryticatus can be related to the tumor microenvironment to some extent. B. batryticatus may exert its anti-cancer effects and improve prognosis of patients by regulating macrophages M1 in VIR and NVIR through acting on different targets.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Condition:   Hepatocellular Carcinoma (HCC) Interventions:   Radiation: Yttrium-90 Radiation Segmentectomy;   Radiation: Stereotactic Body Radiation Therapy Sponsor:   Indiana University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
The World Health Organization (WHO) classifies neuroendocrine neoplasms as well-differentiated neuroendocrine tumors (either the primary tumor or metastasis) and poorly differentiated neuroendocrine carcinomas.Historically, well-differentiated neuroendocrine tumors have been referred to as “carcinoid tumors,” a term which may cause confusion because clinically a carcinoid tumor is a serotonin-producing tumor associated with functional manifestations of carcinoid syndrome.The use of the term “carcinoid” for neuroendocrine tumor reporting is therefore discouraged for these reasons.Immunohistochemistry...
Source: Oncopathology - Category: Cancer & Oncology Source Type: blogs
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