Saffold cardiovirus infection in a 2-year-old boy with acute pancreatitis.

This report presents a unique case which developed a relapsing acute pancreatitis (AP) after hand, foot and mouth disease and suspected of SAFV-1 infection. A 2-year-old boy was admitted to the hospital because of severe abdominal pain. His serum amylase and lipase levels were elevated. Enhanced computed tomography showed pancreatic swelling and dilation of main pancreatic duct, leading to the diagnosis of severe AP. The viral genome of SAFV-1 was detected by RT-PCR from fecal samples. Furthermore, serum neutralization titer against SAFV was elevated during the AP and decreased after 1 year. These findings strongly suggest the patient developed an SAFV-1 infection concurrent with AP. Therefore, we propose a cohort study is required to clarify a relation between SAFV and the AP hereafter.
PMID: 27000454 [PubMed - as supplied by publisher]

Source: Japanese Journal of Infectious Diseases - March 17, 2016 Category: Infectious Diseases Authors: Ito H, Miyagaki S, Sakaue S, Matsui F, Katsumi Y, Otabe O, Torii J, Itagaki T, Himeda T, Okuwa T, Ohara Y Tags: Jpn J Infect Dis Source Type: research