N-octanoyl dopamine treatment exerts renoprotective properties in acute kidney injury but not in renal allograft recipients

Conclusions
NOD treatment reduces renal injury in warm ischaemia, but is not effective in renal transplant in our experimental animal models. The salutary effect of NOD appears to be TPRV1-dependent, not involving large changes in renal perfusion.

Source: Nephrology Dialysis Transplantation - March 22, 2016 Category: Urology & Nephrology Authors: Klotz, S., Pallavi, P., Tsagogiorgas, C., Zimmer, F., Zöllner, F. G., Binzen, U., Greffrath, W., Treede, R.-D., Walter, J., Harmsen, M. C., Krämer, B. K., Hafner, M., Yard, B. A., Hoeger, S. Tags: BASIC SCIENCE Source Type: research