Decreased blood vessel leakage can improve cancer therapy and reduce tumor spread

(Uppsala University) Cancer therapy is often hampered by the accumulation of fluids in and around the tumor, which is caused by leakage from the blood vessels in the tumor. Researchers at Uppsala University now show how leakage from blood vessels is regulated. They have identified a novel mechanism whereby leakage can be suppressed to improve the result of chemotherapy and reduce the spread of tumors in mice. The results have been published in the scientific journal Nature Communications.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news

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Publication date: December 2018Source: Biomedicine &Pharmacotherapy, Volume 108Author(s): Charlette Tiloke, Krishnan Anand, Robert M. Gengan, Anil A. ChuturgoonAbstractCancer is classified as one of the leading causes of global mortality. It has affected millions of people, often with poor prognosis. Having severe side-effects with conventional chemotherapy, alternate drugs and therapies are actively being investigated. There is a need for innovative drug discovery and design as existing cancer therapies are costly and not readily available. Ayurveda and traditional medicine have utilised natural resources such as plan...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
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Source: Wiener Medizinische Wochenschrift - Category: General Medicine Source Type: research
UCLA researchers have discovered  genetic similarities between the adult stem cells responsible for maintaining and repairing epithelial tissues — which line all of the organs and cavities inside the body — and the cells that drive aggressive epithelial cancers. Their findings could bring about a better understanding of how ag gressive, treatment-resistant cancers develop and progress, and could eventually lead to new drugs for a range of advanced epithelial cancers such as lung, prostate and bladder cancers. The study, led by senior authors Owen Witte and Thomas Graeber, both of the  UCLA E...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
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Source: Chemical Engineering Journal - Category: Chemistry Source Type: research
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Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
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Source: Recent Patents on Anti-Infective Drug Discovery - Category: Infectious Diseases Tags: Recent Pat Antiinfect Drug Discov Source Type: research
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Source: Health Physics - Category: Physics Authors: Tags: Int J Radiat Oncol Biol Phys Source Type: research
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Source: Journal of Oncology - Category: Cancer & Oncology Tags: J Oncol Source Type: research
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Source: Journal of Palliative Care - Category: Palliative Care Tags: J Palliat Care Source Type: research
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Source: Oncology Tube - Category: Cancer & Oncology Source Type: podcasts
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