High-Risk Lung Cancer Patients May Not Need Annual Screenings

Contact: Sarah Avery Phone: 919-660-1306 Email: sarah.avery@duke.edu https://www.dukehealth.org FOR IMMEDIATE RELEASE on Monday, March 21, 2016 DURHAM, N.C. – Most high-risk lung cancer patients might not need annual low-dose computed tomography (LDCT) screenings if they are cleared of disease in their initial test, according to a study led by a Duke Cancer Institute researcher. The researchers found that even former heavy smokers appear to have a reduced incidence of lung cancer if their initial LDCT screening is negative, suggesting that less frequent screening might be warranted.  “This has significant public policy implications,” said Edward F. Patz, Jr., M.D., the James and Alice Chen Professor of Radiology at Duke and lead author of a study published online March 21 in The Lancet Oncology journal. “Not screening patients annually could save millions in health care costs and spare patients the radiation exposure and the downstream effects of false positive screenings." Patz and colleagues analyzed data from the National Lung Screening Trial, a large prospective study that randomly assigned former smokers to either receive three annual low-dose CT scans or three chest radiographs for the early detection of lung cancer. Patients were ages 55-74 who had smoked for the equivalent of 30 years (one pack a day for 30 years, two packs a day for 15 years, etc.). The researchers identified study participants in the CT-scan group whose initial scre...
Source: DukeHealth.org: Duke Health Features - Category: Pediatrics Tags: Duke Medicine Source Type: news

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The follow-up for radically treated non-small cell lung cancer (NSCLC) patients remains controversial. The aim of this study was to review the outcomes since the change in the local protocol in 2014 were CT scan follow-up introduced, in term of further radical treatment for recurrence as well as 3 years survival.243 patients with NSCLC who treated radically with surgical resection were retrospectively reviewed. Patients treated in 2012-2013 were followed-up by chest radiographs or no specific protocol (Group A), while patients treated in 2015 had CT-Scans follow-up at 6, 12 and 18 months (Group B).Out of 169 patients in gr...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Lung cancer Source Type: research
Introduction: In patients with suspected lung cancer a CT scan should be the initial diagnostic test after chest radiography.Objective: To assess the impact of direct access to CT prior to the first appointment in a rapid access lung cancer clinic on diagnostic and treatment delays.Methods: We analysed patients with suspected lung cancer referred from May 2015 to December 2018. General practitioners and specialists from our health department may request a CT at the time of referral and we use a fast track system to offer patients a CT scan scheduled within 1 week. Information was collected on patient characteristics, date ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Lung cancer Source Type: research
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Source: Journal of X-Ray Science and Technology - Category: Radiology Tags: J Xray Sci Technol Source Type: research
Haibo Hu Lung cancer is one of the major causes of cancer-related deaths due to its aggressive nature and delayed detections at advanced stages. Early detection of lung cancer is very important for the survival of an individual, and is a significant challenging problem. Generally, chest radiographs (X-ray) and computed tomography (CT) scans are used initially for the diagnosis of the malignant nodules; however, the possible existence of benign nodules leads to erroneous decisions. At early stages, the benign and the malignant nodules show very close resemblance to each other. In this paper, a novel deep learning-bas...
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research
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A 52-Year-Old Woman With an Abdominal Mass, Bilateral Pulmonary Nodules, and Mediastinal and Hilar Lymphadenopathy. Chest. 2019 Jun;155(6):e175-e178 Authors: Van Treeck BJ, Gehlbach DA, Foster GH, Utz JP, Aubry MC, Colby TV, Yi ES Abstract CASE PRESENTATION: A 52-year-old, nonsmoking, African-American woman with a history of obesity, hypertension, and rheumatoid arthritis was referred for workup of multiple bilateral pulmonary nodules. The pulmonary nodules were discovered incidentally while undergoing a CT scan for an abdominal mass that was radiographically diagnosed as a uterine leiomyoma. She...
Source: Chest - Category: Respiratory Medicine Authors: Tags: Chest Source Type: research
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Introduction Current guidelines recommend invasive mediastinal staging in patients with centrally located radiographic stage T1N0M0 nonsmall cell lung cancer (NSCLC). The lack of a specific definition of a central tumour has resulted in discrepancies among guidelines and heterogeneity in practice patterns. Methods Our objective was to study specific definitions of tumour centrality and their association with occult nodal disease. Pre-operative chest computed tomography scans from patients with clinical (c) T1N0M0 NSCLC were processed with a dedicated software system that divides the lungs in thirds following vertical and ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Lung imaging, Lung cancer Original Articles: Lung cancer Source Type: research
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