Individual and Familial Susceptibility to MPTP in a Common Marmoset Model for Parkinson's Disease.

CONCLUSION: Our findings show that low-dose MPTP treatment in marmosets represents a clinically relevant PD model, with a window of opportunity to examine the onset of the disease, allowing the detection of individual variability in disease susceptibility, which may be of relevance for the diagnosis and treatment of PD in humans.
PMID: 26999593 [PubMed - as supplied by publisher]

Source: Neuro-Degenerative Diseases - March 21, 2016 Category: Neurology Authors: Franke SK, van Kesteren RE, Hofman S, Wubben JA, Smit AB, Philippens IH Tags: Neurodegener Dis Source Type: research