Linking MedDRA ® -Coded Clinical Phenotypes to Biological Mechanisms by the Ontology of Adverse Events: A Pilot Study on Tyrosine Kinase Inhibitors

Conclusion By expanding the existing OAE ontological design, our TKI use case demonstrated that the combination of OAE and MedDRA® provides a semantic framework to link clinical phenotypes of adverse drug events to biological mechanisms.
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research