Linking MedDRA ® -Coded Clinical Phenotypes to Biological Mechanisms by the Ontology of Adverse Events: A Pilot Study on Tyrosine Kinase Inhibitors
Conclusion
By expanding the existing OAE ontological design, our TKI use case demonstrated that the combination of OAE and MedDRA® provides a semantic framework to link clinical phenotypes of adverse drug events to biological mechanisms.
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research
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