First clinical trial of specific IKACh blocker shows no reduction in atrial fibrillation burden in patients with paroxysmal atrial fibrillation: pacemaker assessment of BMS 914392 in patients with paroxysmal atrial fibrillation
Conclusion
BMS 914932 has not been shown to reduce AF burden in patients with PAF and pacemakers using beat-to-beat pacemaker monitoring throughout the study. BMS 914392 was well tolerated and did not affect QTc or reduce heart rate.
Trial registration
Clinicaltrials.gov: NCT01356914.
Source: Europace - Category: Cardiology Authors: Podd, S. J., Freemantle, N., Furniss, S. S., Sulke, N. Tags: Atrial fibrillation Source Type: research