CTGF mediates high-glucose induced epithelial-mesenchymal transition through activation of β-catenin in podocytes.

Conclusion CTGF and β-catenin are involved in the EMT of podocytes in diabetes. CTGF mediates high-glucose induced EMT through activation of β-catenin in podocytes. CTGF inhibition may protect podocytes from EMT in diabetes. PMID: 26984259 [PubMed - as supplied by publisher]
Source: Renal Failure - Category: Urology & Nephrology Tags: Ren Fail Source Type: research