Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry as a First-Line Diagnostic Modality in Bacterial Meningitis and Septicemia: a Report of Five Cases

The matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) technology has been shown to be a cost-effective, efficient, and reliable system for performing bacterial identifications. It has a number of potential advantages in clinical care. Here, we describe five life-threatening infections caused by either Listeria monocytogenes or Neisseria meningitidis that were diagnosed by using the MALDI-TOF MS system. The system proved particularly useful when the Gram-stained-smear results were misleading or inconclusive.

Source: Clinical Microbiology Newsletter - March 19, 2016 Category: Microbiology Authors: Priya Nori, Wendy Szymczak, Connie Park, Philip Gialanella, Iona Munjal, Philip Chung, Yi Guo, Julie Williamson, Belinda Ostrowsky, Michael Levi Tags: Case Report Source Type: news