I Am My Mother's Chimera. Chances Are, So Are You.
For years the concept of a "genetic chimera" -- an individual with two genetically distinct cells lines in his/her body -- has sparked the imagination of writers: from Stephen King to Michael Crichton, from CSI to The Office. The idea that an individual could harbor his/her own twin is creepy and intriguing at the same time. Recent advances in DNA sequencing technology have allowed us to probe much deeper into a person's genome, to the point that today scientists believe that chimerism could be far more common than what we originally thought. Chances are, you could be your own twin. But how surprised would you be if I told you that you are actually far more likely to be your mother's chimera than your unborn sibling's? Before the 1960s, it was believed that the placenta was a perfect barrier between mother and fetus, and no blood or cells could trespass it in either direction. Today we know that there's actually a two-way exchange of cells between mother and fetus during pregnancy. What's even more surprising is that these "extraneous" cells outlast the duration of the pregnancy and can in fact be found in the child and/or the mother years after birth. Male DNA has been found in women years after they had given birth to their sons. In fact, fetal cells are released in high quantities during spontaneous abortions, hence can be found even in women who have never delivered, so long as at some point in their lives they became pregnant. Conversely, maternal...
Publication date: Available online 20 August 2018Source: Biocybernetics and Biomedical EngineeringAuthor(s): R. Sumathi, M. Venkatesuslu, Sridhar P. Arjunan
Mona Randolph, 82, of Missouri, is only one of three polio survivors left in the US that uses an iron lung machine, which is no longer made and leaves her with responsibility of repair and maintenance.
Publication date: Available online 20 August 2018Source: NeurocomputingAuthor(s): Junjie Zhang, Yong Xia, Haoyue Zeng, Yanning ZhangAbstractDetection of pulmonary nodules on chest CT is an essential step in the early diagnosis of lung cancer, which is critical for best patient care. In this paper, we propose an automated pulmonary nodule detection algorithm, denoted by NODULe, which jointly uses a conventional method for nodule detection and a deep learning model for genuine nodule identification. Specifically, we first use multi-scale Laplacian of Gaussian (LoG) filters and prior shape and size constraints to detect nodul...
ConclusionLow PNI predicts poor survival in LC patients.
Resistance training (RT) does not seem to reduce the bone-thinning effects of weight loss in older adults, new research shows.Reuters Health Information
CONCLUSIONS: This study shows that IHC with the tested antiserum increases the sensitivity of the diagnosis and may be recommended for routine use in EMB analyses of cardiac transplant patients with Chagas disease.
CONCLUSIONS Our finding revealed that resistance against amphotericin B, itraconazole, ketoconazole, posaconazole, and fluconazole can be observed in C. albicans.
CONCLUSIONS These results demonstrated that NRG-1 can promote recovery of nerve function in brachial plexus injury after contralateral C7 nerve root transfer in rats. PMID: 30121695 [PubMed - in process]
There's a big survival gap between white and minority children when it comes to some childhood cancers. It turns out growing up in poverty explains a lot of the difference.(Image credit: FS Productions/Blend Images/Getty Images)
The findings by Columbia University add to the large body of evidence linking factors like education, income and access and affordability of care to worse survival rates for cancer.
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