Modulators of right ventricular apoptosis and contractility in a rat model of pulmonary hypertension

Conclusion
These results suggest that RV decompensation is associated with the death of cardiomyocytes, resulting in fibrosis. However, the remaining myocytes are capable of sustaining RV contractility through the mechanism that involves CSQ2.

Source: Cardiovascular Research - March 18, 2016 Category: Cardiology Authors: Zungu-Edmondson, M., Shults, N. V., Wong, C.-M., Suzuki, Y. J. Tags: Integrative physiology and pathophysiology Source Type: research