Oropharyngeal squamous cell carcinomas differentially express granzyme inhibitors

Conclusion HPV-positive OPSCCs with a low count of CD3+ TILs or high expression of SERPINB1 have a worse OS, comparable with HPV-negative OPSCCs. This suggests that the immune system plays an important role in the carcinogenesis of the virally induced oropharynx tumors.
Source: Cancer Immunology, Immunotherapy - Category: Cancer & Oncology Source Type: research