Mesenchymal stromal cells in renal transplantation: opportunities and challenges

Nature Reviews Nephrology 12, 241 (2016). doi:10.1038/nrneph.2016.7 Authors: Federica Casiraghi, Norberto Perico, Monica Cortinovis & Giuseppe Remuzzi Lifelong immunosuppressive therapy is essential to prevent allograft rejection in transplant recipients. Long-term, nonspecific immunosuppression can, however, result in life-threatening complications and fail to prevent chronic graft rejection. Bone marrow (BM)-derived multipotent mesenchymal stromal cells (MSCs) have emerged as a potential candidate for cell-based therapy
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Review Source Type: research