Abstract A59: Prognostic relevance of PTEN and TP53 deletion in breast cancer

In conclusion, our data support a role of PTEN and TP53 deletions in breast cancer. However, only PTEN deletion is inked to aggressive tumor behavior, while TP53 deletion has no prognostic relevance in breast cancer.Citation Format: Martina Kluth, Anette Lebeau, Isabell Witzel, Sven Mahner, Linn Woelber, Stefan Geist, Peter Paluchowski, Christian Wilke, Uwe Heilenkoetter, Volkmar Mueller, Ronald Simon, Guido Sauter, Luigi Terracciano, Rainer Krech, Albert von der Assen, Eike Burandt, Patrick Lebok. Prognostic relevance of PTEN and TP53 deletion in breast cancer. [abstract]. In: Proceedings of the AACR Special Conference on Advances in Breast Cancer Research; Oct 17-20, 2015; Bellevue, WA. Philadelphia (PA): AACR; Mol Cancer Res 2016;14(2_Suppl):Abstract nr A59.

Source: Molecular Cancer Research - February 29, 2016 Category: Cancer & Oncology Authors: Kluth, M., Lebeau, A., Witzel, I., Mahner, S., Woelber, L., Geist, S., Paluchowski, P., Wilke, C., Heilenkoetter, U., Mueller, V., Simon, R., Sauter, G., Terracciano, L., Krech, R., Assen, A. v. d., Burandt, E., Lebok, P. Tags: Other Topics: Poster Presentations - Proffered Abstracts Source Type: research