Abstract IA25: Deep sequencing of circulating tumor DNA for personalized cancer detection and monitoring

Circulating tumor DNA (ctDNA) represents a promising biomarker for sensitive, specific, and dynamic detection of disease burden in cancer patients. Additionally, ctDNA analysis allows non-invasive access to cancer genomes and therefore can be used for non-invasive tumor genotyping and monitoring of resistance mutations. In this presentation I will describe technical aspects of ctDNA detection and emerging clinical results from recent studies employing ctDNA analysis.Citation Format: Max Diehn. Deep sequencing of circulating tumor DNA for personalized cancer detection and monitoring. [abstract]. In: Proceedings of the AACR Special Conference on Advances in Breast Cancer Research; Oct 17-20, 2015; Bellevue, WA. Philadelphia (PA): AACR; Mol Cancer Res 2016;14(2_Suppl):Abstract nr IA25.

http://mcr.aacrjournals.org/cgi/content/short/14/2_Supplement/IA25?rss=1

Source: Molecular Cancer Research - February 29, 2016 Category: Cancer & Oncology Authors: Diehn, M. Tags: Monitoring Metastasis and CTCs: Oral Presentations - Invited Abstracts Source Type: research