Abstract IA20: Genomics of a STAT1 knockout mouse model of human ER+ breast cancer

In conclusion, truncating mutations of Prlr drive tumor development in a model of human ERa+ breast cancer and should be considered as novel antitumor targets.Citation Format: Elaine Mardis, Obi L. Griffith, Ruby Chan Szeman, Malachi Griffith, Kilannin Krysiak, Zachary Skidmore, Jasreet Hundal, Julie A. Allen, Arthur Cora, Alexander P. Miceli, Heather Schmidt, Lee Trani, Krishna-Latha Kanchi, Christopher A. Miller, David E. Larson, Robert S. Fulton, Richard K. Wilson, Robert D. Schreiber. Genomics of a STAT1 knockout mouse model of human ER+ breast cancer. [abstract]. In: Proceedings of the AACR Special Conference on Advances in Breast Cancer Research; Oct 17-20, 2015; Bellevue, WA. Philadelphia (PA): AACR; Mol Cancer Res 2016;14(2_Suppl):Abstract nr IA20.

Source: Molecular Cancer Research - February 29, 2016 Category: Cancer & Oncology Authors: Mardis, E., Griffith, O. L., Szeman, R. C., Griffith, M., Krysiak, K., Skidmore, Z., Hundal, J., Allen, J. A., Cora, A., Miceli, A. P., Schmidt, H., Trani, L., Kanchi, K.-L., Miller, C. A., Larson, D. E., Fulton, R. S., Wilson, R. K., Schreiber, R. D. Tags: Animal Models: Oral Presentations - Invited Abstracts Source Type: research