Hawaii tries to ward off Zika amid pesticide fears and limited resources

On a farm in the heart of Hawaii's ongoing dengue outbreak, coffee grows wild among the ferns, and vanilla vines climb guava trees. It's hard to know where nature ends and the farm begins, and that's the way organic farmers there like it. But state efforts to combat the outbreak — and prevent the...
Source: Los Angeles Times - Science - Category: Science Authors: Source Type: news

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This study examined 2014–2016 Zika and dengue epidemic data at the sub-national level to characterise transmission across the Dominican Republic. For each municipality, spatio-temporal mapping was used to characterise disease burden, while data were age and sex standardised to quantify burden distributions among the population. In separate analyses, time-ordered data were combined with the underlying disease migration interval distribution to produce a network of likely transmission chain events, displayed using transmission chain likelihood matrices. Finally, municipal-specific reproduction numbers (Rm) were est...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Med Clin (Barc). 2022 Jan 10:S0025-7753(21)00668-0. doi: 10.1016/j.medcli.2021.10.014. Online ahead of print.ABSTRACTOver the last two decades there has been an increase in outbreaks of arboviral diseases, being Spain at high risk for disease emergence. This paper reviews the current evidence regarding the transmissibility, disease epidemiology, control strategies and mosquito-borne disease drivers and maintaining factors in Spain. There is risk of autochthonous cases and outbreaks in Spain due to recent transmission occurrence. Recently, there has been an expansion of Aedes Albopticus, a vector for Dengue, Zika and Chikun...
Source: Medicina Clinica - Category: General Medicine Authors: Source Type: research
Conclusion: The current study provided a list of African medicinal plants which demonstrated antiviral activities and could potentially be candidates for COVID-19 treatment. However, all studies were preliminary and in vitro screening. Further in vivo studies are required for plant-based management of viral diseases.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
In this study, we unravel ZIKV NS4B as antagonist of the IFN signaling cascade. Firstly, we reported the genomic characterization of NS4B isolated from a strain of the 2016 outbreak, ZIKV Brazil/2016/INMI1, and we predicted its membrane topology. Secondly, we analyzed its phylogenetic correlation with other flaviviruses, finding a high similarity with dengue virus 2 (DEN2) strains; in particular, the highest conservation was found when NS4B was aligned with the IFN inhibitory domain of DEN2 NS4B. Hence, we asked whether ZIKV NS4B was also able to inhibit the IFN signaling cascade, as reported for DEN2 NS4B. Our results sho...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
J Vector Borne Dis. 2021 Jan-Mar;58(1):1-11. doi: 10.4103/0972-9062.318313.ABSTRACTIncreased outbreaks of mosquito borne diseases like the deadly parasitic disease, malaria and arboviruses like Zika, yellow fever and dengue viruses around the world have led to increased interest in traps that could effectively be used against mosquitoes. For example, a Google search at the time of this writing, asking, 'which is the best way of trapping mosquitoes?' produced 35.5 million search results. Regardless of the interest in the subject, scientists have yet to find a definitive answer to these questions. One area that has been expl...
Source: Journal of Vector Borne Diseases - Category: Infectious Diseases Authors: Source Type: research
by Jonathan R. Hernandez, Michael Longnecker, Chris L. Fredregill, Mustapha Debboun, Patricia V. PietrantonioAedes aegypti (L.) is an important mosquito vector of emerging arboviruses such as Zika, dengue, yellow fever, and chikungunya. To quell potential disease outbreaks, its populations are controlled by applying pyrethroid insecticides, which selection pressure may lead to the development of insecticide resistance. Target site insensitivity to pyrethroids caused by non-synonymous knockdown resistance (kdr) mutations in the voltage-gated sodium (NaV) channel is a predominant mechanism of resistance in mosquitoes. To eva...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Dr Ijaz Ali has spent the last 11 years persuading the authorities to use genetically engineered mosquitoes to fight dengue fever. The health department, however, is concerned about unforeseen circumstances that could arise from this method. By Zofeen EbrahimKarachi , Nov 2 2021 (IPS) Twenty-three-year-old Sarah Tajammal felt a sense of “impending doom” as she fought high fever, nausea, bouts of vomiting and extreme fatigue after being diagnosed with dengue two weeks back. Living in Lahore’s DHA area, which has reported the most dengue cases “because of the damp green environment”, she may ha...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Asia-Pacific Development & Aid Environment Featured Headlines Health Human Rights Humanitarian Emergencies Inequity TerraViva United Nations Source Type: news
This study confirms that the DENV and ZIKV infection patterns of nineAe.aegypti field populations found in geographically separate health districts of an endemic Brazilian city vary. We analyzed the infection rate, disseminated infection, vector competence, and viral load through quantitative PCR. Mosquitoes were challenged using the membrane-feeding assay technique and were tested seven and fourteen days post-infection (early and late infection phases, respectively). The infection responses varied among theAe.aegypti populations for both flaviviruses in the two infection phases. There was no similarity between DENV and ZI...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
DISCUSSION: Our study shows a high proportion of donors who are viraemic and asymptomatic, especially during outbreaks, with prevalences surpassing 5% for DENV, 1% for CHIKV, and 2% for ZIKV. These data confirm a clear threat to blood transfusion safety. The elevated seroprevalence for these three arboviruses is also indicative of their wide circulation in populations, correlating with an increased risk of infected but asymptomatic donors. Health centres and institutions must address this threat, especially in tropical regions where the biggest outbreaks occur.PMID:34694219 | DOI:10.2450/2021.0106-21
Source: Blood Transfusion - Category: Hematology Authors: Source Type: research
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