Evaluation of the Alere-i Influenza A&B assay for Rapid Identification of Influenza A and Influenza B Viruses.

This study was conducted in order to study the performance of Alere-i Influenza A&B assay compared to molecular techniques, considered as gold standard methods to evaluate the results. A total of 119 nasopharyngeal swabs collected from inpatients with influenza-like illness were included in the study using both archived and prospectively collected samples from adults and children. Prospectively collected samples were also compared to Alere BinaxNOW® Influenza A & B Card. The overall sensitivity for detection of Influenza A and B viruses compared to those of molecular techniques were 65.96% and 53.33% respectively, while the specificity were 98.51% and 95.96%. Compared to Alere BinaxNOW® Influenza A & B Card, the Alere-i assay is considerably more sensitive for detection of influenza A and B viruses, although both tests demonstrated excellent specificity for diagnosis of Influenza viruses. PMID: 26967368 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research